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Basic information

CohesinDB ID: CDBP00419311

Locus: chr21-38861132-38861513

Data sourse: ENCSR230ZWH, ENCSR000EHX, ENCSR000BLY, ENCSR879KXD

Cell type: K-562, Liver, SK-N-SH

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 63%, "14_ReprPCWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, HMG20A, MEIS2, XBP1, FOXA1, PBX2, UBTF, RXRB, ZFHX2, TFAP4, HDGF, LYL1, ATF3, RUNX3, CBFB, SMARCE1, JMJD1C, ELF1, TRIM28, RBM39, SNAI2, LMO2, ESR1, OCA2, MLL, PITX3, USF2, CTCF, TCF12, JUN, EP300, ARID5B, LMO1, SOX5, GATA6, DPF2, E2F6, IRF4, CREB3, SOX6, RFX3, TEAD4, FOXA3, KMT2B, GATAD2A, PDX1, RBPJ, TFAP2C, EED, GLIS1, POU2F2, CHD8, MYCN, ZNF263, POU5F1, CDK7, RUNX1T1, CTBP1, MTA2, ZBTB17, ZBTB48, ZNF317, STAT1, TOP2A, ZNF205, GATAD1, SAP130, ERG2, ERG, PBX1, ETS1, MYC, SMARCA4, RFX1, ARID1B, RAD21, HOMEZ, GRHL3, NKX2-1, GABPA, STAT3, XRCC5, ZNF614, ZNF398, IKZF1, RCOR1, NFE2, NR2F6, NR3C1, ESRRA, CEBPB, KMT2A, CREB1, TBL1XR1, EZH2, EBF3, GABPB1, ZNF436, SPI1, ZNF257, HDAC2, GATA2, INTS13, FLI1, DRAP1, NR2C2, ZGPAT, HEXIM1-CDK9, NFIL3, ZNF554, ETV5, RUNX1, BCL6, HDAC1, CEBPA, SOX13, ZFX, SMAD3, TET2, ERG3, RARA, CREBBP, NOTCH1, RUNX2, CDK6, GATA4, NRF1, ARNT, SOX11, ZNF48, ATF2, SMAD4, CBFA2T3, SMARCB1, FOS, SNRNP70, CDK8, MED1, TEAD3, CEBPD, MYB, ZMYM3, L3MBTL2, GTF3C2, SETDB1, EVI1, TBX5, BCL11A, NR4A1, NKX2-5, REST, ZBTB7A, ZNF479, RBM25, ATF7, POU2F3, BCOR, TCF3, NCOR2, STAG1, ETV4, TRP47, CBFA2T2, ZNF283, MEF2B, FOXA2, MTA3, TBL1X, CHD2, CREM, CBX3, EBF1, ZSCAN16, WT1, ZBTB33, MEF2C, CDK9, ZNF580, ZKSCAN1, HOXB13, KDM1A, YY1, RELA, ZNF148, JUNB, SP140, ZFP36, ZIC2, TCF4, HIF1A, OTX2, GATA3, TAL1, MAX, GATA1, ZNF143, HAND2, KLF4, ZNF592, SP7, GFI1B, BCL11B, NCOA3, PKNOX1, MED, ZNF334, EGR2, BHLHE40, AR, ZBTB16, ZBTB40, HEXIM1, ZBTB26, RNF2, NCOR1, BRD4, JUND, SCRT1, MAZ, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): PCP4,GET1-SH3BGR,ERG,B3GALT5,GET1,PSMG1,LCA5L

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000157554, ENSG00000183527, ENSG00000285815, ENSG00000182093, ENSG00000157578, ENSG00000183778, ENSG00000183036,

eachgene

Deatailed information for cohesin site CDBP00419311