- Basic information
- CohesinDB ID: CDBP00419317
- Locus: chr21-38873491-38873832
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Data sourse: GSE206145-NatGen2015, GSE86191
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Cell type: Fibroblast, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 81%,
"14_ReprPCWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, NOTCH1, OGG1, JMJD1C, PPARG, BRD1, TRIM28, CEBPA, CEBPB, ZFX, ESR1, WT1, ZSCAN5A, DUX4, SOX11, ZBTB48, MAZ, CTCF, SPI1, NFE2
- Target gene symbol (double-evidenced CRMs): GET1,B3GALT5,LCA5L,GET1-SH3BGR,ERG,PCP4,PSMG1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000157554,
ENSG00000183527,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
ENSG00000183778,
ENSG00000183036,
- Related loop:
chr21:27500000-27525000~~chr21:38850000-38875000,
chr21:38475000-38500000~~chr21:38875000-38900000,
chr21:38500000-38525000~~chr21:38850000-38875000,
chr21:38525000-38550000~~chr21:38850000-38875000,
chr21:38525000-38550000~~chr21:38875000-38900000,
chr21:38575000-38600000~~chr21:38850000-38875000,
chr21:38725000-38750000~~chr21:38850000-38875000,
chr21:38725000-38750000~~chr21:38875000-38900000,
chr21:38850000-38875000~~chr21:39050000-39075000,
chr21:38850000-38875000~~chr21:39100000-39125000,
chr21:38850000-38875000~~chr21:39150000-39175000,
chr21:38850000-38875000~~chr21:39400000-39425000,
chr21:38850000-38875000~~chr21:39600000-39625000,
chr21:38850000-38875000~~chr21:39850000-39875000,
chr21:38875000-38900000~~chr21:39025000-39050000,
chr21:38875000-38900000~~chr21:39050000-39075000,
chr21:38875000-38900000~~chr21:39100000-39125000,
chr21:38875000-38900000~~chr21:39150000-39175000,