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Basic information

CohesinDB ID: CDBP00419319

Locus: chr21-38875623-38877038

Data sourse: GSE67783, GSE86191, GSE72082, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE111537

Cell type: MCF-7, RPE, Fibroblast, HCT-116, K-562, OCI-AML-3, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: NIPBL,SA1,Rad21,SA2,Mau2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 74%, "7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, FOXO1, NCOA2, FOSL1, CHD8, CEBPA, POU5F1, MYCN, CDK7, KDM4C, ZFX, SOX13, XBP1, ZSCAN21, ZBTB48, ZSCAN5A, STAT1, FOXA1, WT1, CDK9, HOXB13, TBP, PRDM10, ERG, RELA, NOTCH1, JUNB, BMI1, RUNX2, MYC, SMARCA4, RFX1, ETS1, ATF3, SP140, ARNT, PBX4, GRHL3, HIF1A, ZNF48, GATA3, GABPA, PRDM9, STAT3, MAX, TAL1, CEBPG, CEBPB, JMJD1C, NCOA3, TEAD3, TRIM28, MYB, CEBPD, PIAS1, EZH2, LMO2, ESR1, OCA2, MYOD1, PHOX2B, CTCF, JUN, TCF12, BCL11A, BAF155, LMO1, AR, GATA2, ZNF479, SIX2, HSF1, BRD4, PHIP, PRDM6, MAZ, TEAD4, ZNF554, GATAD2A, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): ERG,PSMG1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 7

Related genes and loops

Related gene: ENSG00000157554, ENSG00000183527,

eachgene

Deatailed information for cohesin site CDBP00419319