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Basic information

CohesinDB ID: CDBP00419320

Locus: chr21-38878486-38879325

Data sourse: ENCSR230ZWH, GSE206145, GSE206145-NatGen2015, GSE120943, ENCSR635OSG, ENCSR000EDE, GSE111537, GSE126755, ENCSR917QNE

Cell type: RPE, Fibroblast, Monocytes, OCI-AML-3, HeLa-S3, Liver, Neutrophil

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: Mau2,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 75%, "9_Het": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, SKI, NFIA, CBX1, PPARG, CEBPA, EBF1, TOP2A, ZFX, XBP1, ZBTB48, WT1, STAT1, FOXA1, MEF2C, ZBTB33, PRDM10, ERG, YY1, RELA, CREBBP, HNF4G, JUNB, ATF3, NFIC, RUNX2, CDK6, MYC, ONECUT1, RAD21, ZFP36, ZIC2, PBX4, ARNT, RXRA, GABPA, STAT3, MAX, FOS, CDK8, MED1, ZNF750, CEBPB, JMJD1C, KLF4, CEBPG, TRIM28, CEBPD, ETV1, NR2F2, ESR1, JUN, SP1, ZNF664, HNF4A, AR, PAX8, RXR, REST, TRIM24, EGR1, MXI1, BRD4, JUND, ZNF350, ZNF554, AHR

Target gene symbol (double-evidenced CRMs): ERG,PSMG1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 43

Related genes and loops

Related gene: ENSG00000157554, ENSG00000183527,

eachgene

Deatailed information for cohesin site CDBP00419320