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Basic information

CohesinDB ID: CDBP00419321

Locus: chr21-38879734-38880718

Data sourse: GSE120943, ENCSR230ZWH, ENCSR917QNE

Cell type: Liver, Monocytes

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 67%, "9_Het": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: THAP11, FOXO1, PGR, FOXA2, CEBPA, HMG20A, LDB1, SOX13, STAT1, FOXA1, HLF, FOXF1, RXRB, KDM1A, YY1, RELA, RARA, HOXC5, ATF3, ZNF626, ZNF280A, ZNF510, GATA4, RAD21, GRHL3, PBX4, DAXX, RXRA, GATA3, SMAD4, GABPA, STAT3, MAX, IKZF1, NR2F6, NR3C1, ESRRA, CEBPB, NCOA3, NR2F2, TRIM28, CEBPG, TEAD3, NR2F1, PIAS1, TP53, SETDB1, MYOD1, PHOX2B, SP1, EP300, SPI1, HNF4A, AR, IRF1, SOX5, REST, GATA2, JUND, BRD4, FOXP1, ZNF350, NFIL3, ZIM3, FOXA3, GATAD2A, FOSL2

Target gene symbol (double-evidenced CRMs): PSMG1,ERG

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000157554, ENSG00000183527,

eachgene

Deatailed information for cohesin site CDBP00419321