- Basic information
- CohesinDB ID: CDBP00419323
- Locus: chr21-38887207-38887702
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Data sourse: GSE206145, GSE110061, GSE131606, GSE86191
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Cell type: HCT-116, HEK293T
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,SMC3,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"9_Het": 77%,
"15_Quies": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBX5, CBX1, CHD8, CBX3, MYCN, SMC1A, TOP2A, TBL1X, ZFX, POU2F2, XBP1, ZSCAN5D, PALB2, ZBTB48, STAT1, FOXA1, WT1, MAFF, BAHD1, ZNF549, ZNF529, KDM1A, RELA, ZNF35, NOTCH1, ZNF626, MYC, ZNF510, ZNF155, ZNF184, ZBTB44, HIF1A, OTX2, SMC3, ZNF143, CDK8, ZNF320, MED1, NCOA3, TRIM28, SCRT2, PIAS1, SNAI2, EZH2, ESR1, C11orf30, MAFG, SETDB1, ZNF561, JUN, CTCF, USF1, BCL11A, MAFK, AR, PAX3-FOXO1, GATA2, ZBTB26, NOTCH3, SCRT1, ZNF528, ZNF350, ZNF280A, HCFC1R1, MAZ, ZNF316, AHR
- Target gene symbol (double-evidenced CRMs): ERG,PSMG1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops