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Basic information

CohesinDB ID: CDBP00419325

Locus: chr21-38894935-38895727

Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE72082, ENCSR703TNG, GSE25021

Cell type: MCF-7, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 86%, "14_ReprPCWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, CBFA2T2, POU2F2, CHD8, TBL1X, FOXA2, RUNX1T1, SIN3A, ZFX, XBP1, ZBTB17, MAFF, ZSCAN5A, FOXA1, HOXB13, ERG, HNRNPK, RELA, CREBBP, ZBTB2, ATF3, MYC, CDK6, AHR, THAP1, ARID1B, PRDM1, GRHL3, HIF1A, ARNT, GATA3, ATF2, GABPA, TAL1, NKX3-1, ZNF143, MED1, TLE3, NR3C1, TEAD3, NCOA3, ETV1, PIAS1, EZH2, ZNF3, ESR1, OCA2, GRHL2, MYOD1, PHOX2B, CTCF, MAFK, BAF155, AR, ZNF257, DPF2, GATA2, ARID1A, NOTCH3, BRD4, SCRT1, CTBP2, FOXP1, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): PSMG1,ERG

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000157554, ENSG00000183527,

eachgene

Deatailed information for cohesin site CDBP00419325