- Basic information
- CohesinDB ID: CDBP00419330
- Locus: chr21-38920487-38927328
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Data sourse: GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, ENCSR000BLY, ENCSR150EFU, ENCSR000ECS, GSE103477, GSE111537, ENCSR330ELC, GSE108869, ENCSR917QNE, ENCSR000EFJ, GSE115602, GSE165895, GSE67783, GSE86191, GSE138405, GSE51234, GSE206145-NatGen2015, GSE120943, GSE138105, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, GSE98367, ENCSR000BLS, GSE206145, GSE85526, ENCSR981FDC, ENCSR247LSH, ENCSR807WAC, ENCSR000EHX, ENCSR620NWG, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, GSE105004, ENCSR853VWZ, GSE131956, GSE129526, ENCSR000HPG, ENCSR676MJK, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE68388, GSE126990, ENCSR748MVX
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Cell type: SLK, Liver, GP5d, HuCC-T1, RPE, Fibroblast, HEKn, HeLa-S3, IMR-90, HFFc6, Monocytes, GBM39, SK-N-SH, RT-112, THP-1, Macrophage, MCF-7, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, A-549, HUVEC, HeLa, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 27% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.711
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"7_Enh": 34%,
"5_TxWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GATA3, GATA2
- Target gene symbol (double-evidenced CRMs): ERG,ETS2,GET1-SH3BGR,GET1
- Function elements
- Human SNPs: Adult_body_size
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 24
- Related genes and loops
- Related gene:
ENSG00000157554,
ENSG00000157557,
ENSG00000285815,
ENSG00000182093,
- Related loop:
chr21:38450000-38475000~~chr21:38900000-38925000,
chr21:38500000-38525000~~chr21:38900000-38925000,
chr21:38575000-38600000~~chr21:38925000-38950000,
chr21:38725000-38750000~~chr21:38900000-38925000,
chr21:38800000-38825000~~chr21:38900000-38925000,
chr21:38900000-38925000~~chr21:39000000-39025000,
chr21:38900000-38925000~~chr21:39025000-39050000,
chr21:38900000-38925000~~chr21:39050000-39075000,
chr21:38900000-38925000~~chr21:39075000-39100000,
chr21:38900000-38925000~~chr21:39125000-39150000,
chr21:38900000-38925000~~chr21:39375000-39400000,
chr21:38925000-38950000~~chr21:39025000-39050000,
chr21:38925000-38950000~~chr21:39050000-39075000,
chr21:38925000-38950000~~chr21:39100000-39125000,
chr21:38925000-38950000~~chr21:39125000-39150000,
chr21:38925000-38950000~~chr21:39375000-39400000,