- Basic information
- CohesinDB ID: CDBP00419334
- Locus: chr21-38933315-38934329
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Data sourse: GSE67783, GSE86191, GSE72082, GSE206145, GSE206145-NatGen2015, ENCSR054FKH, GSE120943
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Cell type: RPE, Fibroblast, HCT-116, Monocytes, Hep-G2, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 67%,
"14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBFA2T2, CHD8, BCL6, CEBPA, MYCN, RBBP5, FOXA2, SOX13, ZFX, XBP1, ZBTB48, WT1, ZSCAN5A, FOXA1, GATAD1, SAP130, SUZ12, ETV5, RXRB, DDX5, ZNF300, YY1, RARA, ZNF90, HOMEZ, RAD21, ZNF48, SMAD4, GABPA, XRCC5, MAX, CHD1, MIER3, CBX2, TEAD3, CCAR2, LMO2, OCA2, EGR2, GABPB1, CTCF, ELF3, SPI1, BHLHE40, SOX5, IKZF5, ZNF479, ZBTB26, FOXP1, MAZ, FOXA3, GATAD2A, STAG1, MLX
- Target gene symbol (double-evidenced CRMs): GET1,GET1-SH3BGR,ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops