- Basic information
- CohesinDB ID: CDBP00419336
- Locus: chr21-38936897-38937530
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Data sourse: GSE67783, GSE86191, GSE111913, GSE206145, GSE165895
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Cell type: RPE, HCT-116, RT-112, HSPC, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 64%,
"14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, NME2, XBP1, FOXA1, SUZ12, PBX2, ZFHX2, ATF3, BMI1, ZFP64, CHD7, CBFB, ZNF736, ZNF467, MYOG, ELF1, TRIM28, SNAI2, ESR1, OCA2, CTCF, JUN, EP300, ARID5B, LMO1, ZBTB20, RFX5, ZNF512B, RFX3, SMC1, TEAD4, ZNF175, PDX1, TFAP2C, ZSCAN5D, MYCN, POU5F1, RUNX1T1, ID3, CDK7, CTBP1, ZBTB48, ZSCAN5A, ERG2, ERG, ETS1, MYC, RFX1, RAD21, GRHL3, GABPA, NKX3-1, RCOR1, ZNF750, CEBPB, CREB1, CCAR2, EZH2, SPI1, ZNF786, GATA2, FLI1, MXI1, ETV5, RUNX1, CTNNB1, CEBPA, NKX2-2, SIN3A, ZFX, SMAD3, ERG3, ZNF18, NOTCH1, RUNX2, GATA4, ARNT, ZNF48, PRDM9, ICE2, TEAD3, ZEB1, MYB, ZMYM3, BCL11A, REST, RBM25, BCOR, SMC3, STAG1, WT1, ESR2, FOXF1, CDK9, KDM1A, YY1, RELA, SP140, HIF1A, GATA3, TAL1, MAX, GATA1, HAND2, NR2F1, NEUROG2, KDM5B, TP53, ZSCAN22, EGR2, ZNF140, PHOX2B, AR, ZBTB26, HSF1, NCOR1, BRD4, MAZ, TBX2, AHR
- Target gene symbol (double-evidenced CRMs): ERG,GET1,GET1-SH3BGR
- Function elements
- Human SNPs: Body_size_at_age_10
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops