- Basic information
- CohesinDB ID: CDBP00419339
- Locus: chr21-38942437-38943594
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Data sourse: ENCSR000BLD, GSE67783, GSE72082, GSE111913, ENCSR404BPV, ENCSR198ZYJ, GSE25021
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Cell type: MCF-7, H1-hESC, Neurons-H1, RT-112, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SMC3,Rad21,SA2,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 70%,
"14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, SMC1A, ZSCAN5D, NKX2-2, SIN3A, ZFX, ZSCAN5A, FOXA1, ZNF770, ERG3, ERG2, ZFHX2, RELA, ASCL1, ETS1, MYC, RFX1, RAD21, GRHL3, PRDM9, MAX, XRCC5, GATA1, ZNF143, TEAD3, TEAD1, TRIM28, OCA2, MYOD1, PHOX2B, CTCF, SPI1, EP300, REST, ZBTB26, MXI1, ZNF766, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,ERG,GET1
- Function elements
- Human SNPs: Immune_response_to_smallpox_vaccine_(IL-6)
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops