- Basic information
- CohesinDB ID: CDBP00419345
- Locus: chr21-38962289-38962670
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 53%,
"9_Het": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, HMG20A, ZNF660, MEIS2, HNF1A, PATZ1, FOXA1, HLF, RBFOX2, RXRB, PBX2, MLL4, ZFHX2, TFAP4, ATF3, ZFP64, CHD7, PRDM1, MXD4, SMARCE1, TP63, CDX2, ZNF629, MAF, KLF5, JMJD1C, TRIM28, TEAD1, ETV1, SNAI2, NFE2L2, KLF6, RCOR2, ESR1, LMO2, TP73, HNF1B, HDAC8, MLL, USF2, CTCF, JUN, TCF12, EP300, BAF155, ZNF577, ZBTB20, LMO1, SOX5, GATA6, DPF2, SOX4, DMAP1, E2F6, TRIM24, RFX5, SOX6, U2AF2, ZNF518A, E2F1, ZNF528, TEAD4, FOXA3, ZNF175, GATAD2A, PDX1, RBPJ, MLX, GTF2F1, GLIS1, TFAP2C, POU2F2, MYCN, ZNF263, TOP2A, BRD3, ID3, CTBP1, ZSCAN21, ZBTB48, ZSCAN5A, STAT1, ZNF205, SRF, GATAD1, SAP130, ERG2, TBP, HNF4G, ERG, ZBTB21, ASCL1, NFKB2, ETS1, MYC, SMARCA4, EOMES, HOMEZ, RAD21, ARID1B, GRHL3, RXRA, NKX2-1, GABPA, STAT3, ZNF614, XRCC5, NKX3-1, ZNF398, IKZF1, MIER3, RCOR1, NR2F6, NFE2, VDR, ARNTL, NR3C1, CEBPB, ESRRA, CREB1, KLF8, GRHL2, ZNF652, GABPB1, ZHX2, SPI1, TFE3, MIXL1, KLF17, HDAC2, GATA2, ZNF644, MXD3, SIX2, ZSCAN29, FLI1, DRAP1, ZGPAT, MXI1, NR2C2, E2F5, ZNF490, NFIL3, ZIM3, ZNF554, ETV5, RUNX1, THAP11, BCL6, SMC1A, CEBPA, NKX2-2, HDAC1, LDB1, SOX13, ZFX, ZNF335, POU4F2, AFF4, SMAD3, ERG3, SP5, SMARCC1, PRDM10, RARA, ZNF35, NOTCH1, CREBBP, ZNF384, RUNX2, GATA4, OSR2, ZNF184, DAXX, NRF1, PBX4, ARNT, BACH1, ZNF48, ATF2, SMAD4, ZEB2, HMBOX1, PBX3, CBFA2T3, ZNF10, FOS, CDK8, CHD1, MAFB, MED1, ZNF584, TEAD3, PML, CEBPD, MYB, SCRT2, ZMYM3, ZEB1, VEZF1, SMAD1, NR1H2, ZNF331, MAFG, C11orf30, L3MBTL2, TBX5, SETDB1, STAT5A, KLF16, RBM22, MAFK, BCL11A, SP1, HNF4A, IKZF5, NKX2-5, REST, ARID1A, ARID2, ATF7, ASH2L, ZNF605, ZNF548, PHIP, TCF3, FOXP1, PRDM6, SMC3, ELL2, NCOR2, STAG1, MLLT1, ETV4, ZNF394, CBFA2T2, PPARG, FOXA2, MTA3, ZNF316, EBF1, CREM, MEIS1, MIER2, ZNF692, ZNF600, WT1, MAFF, ZSCAN16, FOXF1, ZNF574, ZBTB33, TCF7, MEF2C, CDK9, KDM1A, YY1, RELA, ZNF589, JUNB, SP140, ZIC2, TCF4, HIF1A, BHLHE22, GATA3, MGA, TAL1, MAX, MAF1, GATA1, ZNF143, HAND2, CEBPG, KLF4, SP7, GFI1B, NR2F2, NEUROG2, NR2F1, KDM5B, TP53, ZBTB6, PKNOX1, ZNF334, NFKB1, MYOD1, EGR2, PHOX2B, BRD2, ELF3, KAT8, BHLHE40, AR, NFKBIZ, ARID4B, TAF1, PAX3-FOXO1, RXR, ZNF366, EGR1, ZBTB26, RNF2, NCOR1, SCRT1, JUND, BRD4, MAZ, TBX2, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): ETS2,ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops