- Basic information
- CohesinDB ID: CDBP00419346
- Locus: chr21-38963077-38964501
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Data sourse: GSE118494, GSE206145-GSE177045, GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, ENCSR153HNT
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Cell type: MCF-7, RPE, Fibroblast, HCT-116, IMR-90, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 58%,
"9_Het": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, MYCN, RFX1, NME2, XBP1, ZBTB48, BRD4, ZSCAN5A, WT1, ZNF334, MAZ, CTCF, PRDM14, STAG1
- Target gene symbol (double-evidenced CRMs): ETS2,ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops