- Basic information
- CohesinDB ID: CDBP00419352
- Locus: chr21-38973691-38974043
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Data sourse: GSE111913, GSE67783, GSE86191, GSE98367
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Cell type: RT-112, HCT-116, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 73%,
"14_ReprPCWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, MYCN, ZFX, ZBTB48, WT1, SUZ12, RXRB, ZNF596, ERG, MYC, ZNF48, PRDM9, TEAD3, ZNF121, ZNF331, ESR1, MYOD1, CTCF, ZHX2, BRD4, NCOA2, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): ETS2,ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops