- Basic information
- CohesinDB ID: CDBP00419353
- Locus: chr21-38976614-38977242
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: RPE, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 62%,
"14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, CBFA2T2, SMC1A, FOXA2, MYCN, RBBP5, ID3, ZFX, ZBTB48, WT1, ZSCAN5A, ERG3, ERG2, PBX2, YY1, ATF3, MYC, SMARCA4, RFX1, EOMES, ZFP36, HIF1A, ZNF48, PRDM9, GABPA, ZNF143, PRDM14, GATA1, NR2F6, MED1, SRSF3, TEAD1, MYB, TP73, EGR2, USF1, AR, GATA2, HSF1, RNF2, HNRNPLL, BRD4, MAZ, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): ETS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops