- Basic information
- CohesinDB ID: CDBP00419354
- Locus: chr21-38979219-38983585
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Data sourse: ENCSR000BLD, GSE105028, GSE103477, GSE111537, GSE165895, ENCSR000BTU, GSE67783, GSE86191, GSE138405, GSE206145-NatGen2015, GSE138105, GSE130135, GSE98367, GSE206145, ENCSR000ECE, GSE97394, ENCSR000HPG, GSE111913, ENCSR000EDE, GSE68388, GSE126990, GSE64758
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Cell type: MDM, SLK, HuCC-T1, H9-hESC, RPE, Fibroblast, Ishikawa, HeLa-S3, IMR-90, HFFc6, H1-hESC, RT-112, THP-1, Macrophage, HUES64, Hela-Kyoto, HCT-116, HEK293T, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 10% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.778
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES,Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"7_Enh": 24%,
"15_Quies": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, SOX2, MEIS2, XBP1, FOXA1, SUZ12, PBX2, ZFHX2, ATF3, NFIC, THAP1, CHD7, RUNX3, ZNF322, MAF, JMJD1C, TEAD1, TRIM28, ELF1, SNAI2, NFE2L2, SAP30, ESR1, MLL, TP73, LMO2, CTCF, TCF12, JUN, EP300, ARID5B, ZBTB20, LMO1, DPF2, PAX8, E2F6, TRIM24, IRF4, TEAD4, KMT2B, ZNF92, RBPJ, GLIS1, JARID2, NANOG, CHD8, BRD1, POU2F2, POU5F1, MYCN, TOP2A, KDM4C, CDK7, ZNF263, MTA2, ZBTB48, DUX4, STAT1, SRF, ERG2, ERG, PBX1, MYC, EOMES, SMARCA4, RAD21, GRHL3, NKX2-1, GABPA, PRDM14, IKZF1, GFI1, RCOR1, VDR, ZNF750, CEBPB, NR3C1, STAT5B, KMT2A, CREB1, EZH2, BMPR1A, ZNF436, ZHX2, SPI1, GATA2, GATAD2B, SIX2, MXI1, SMARCA5, RELB, RUNX1, SMC1A, CEBPA, SIN3A, ZFX, SMAD3, ERG3, TWIST1, RARA, ZNF35, NOTCH1, ZNF384, SMAD2, OSR2, ZNF184, ARNT, PBX4, ATF2, SMAD4, FOXM1, FOS, CDK8, CHD1, MED1, TEAD3, MYB, SCRT2, ZMYM3, NCOA1, STAT5A, MAFK, SP1, NIPBL, BCL11A, ZBTB7A, RBM25, ATF7, ASH2L, HOXA9, CTBP2, PHIP, BCOR, FOXP1, TCF3, AATF, SMC3, MLLT1, STAG1, SKI, CBFA2T2, MEF2B, PPARG, FOXA2, MTA3, EBF1, MEIS1, SS18, TBL1X, ZNF600, ZSCAN16, RBBP5, MAFF, WT1, MEF2C, CDK9, KDM1A, YY1, RELA, JUNB, SP140, ZIC2, TCF4, ZFP36, GATA3, BATF, TAL1, MAX, GATA1, CEBPG, BCL11B, SP7, GFI1B, NR2F2, NR2F1, TCF7L2, KDM5B, TP53, PKNOX1, MED, MYOD1, EGR2, T, ELF3, TBX21, BHLHE40, AR, PAX3-FOXO1, ZBTB16, RXR, YAP1, EGR1, ZBTB26, SCRT1, BRD4, MAZ, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): ETS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 30
- Related genes and loops