- Basic information
- CohesinDB ID: CDBP00419357
- Locus: chr21-38997973-38998636
-
Data sourse: GSE206145-NatGen2015, GSE120943, GSE98367
-
Cell type: Fibroblast, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 42%,
"5_TxWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, CEBPA, SS18, ZFX, CBX8, CDK9, PBX1, ZNF384, MYC, SMARCA4, TCF4, GRHL3, HIF1A, BHLHE22, TAL1, CDK8, CEBPB, TRIM28, KMT2A, MYB, MED, EVI1, BCL11A, SPI1, ZNF157, GATA2, BRD4, TCF3, MLLT1
- Target gene symbol (double-evidenced CRMs): ETS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000157557,
- Related loop:
chr21:38450000-38475000~~chr21:39000000-39025000,
chr21:38575000-38600000~~chr21:39000000-39025000,
chr21:38650000-38675000~~chr21:39000000-39025000,
chr21:38725000-38750000~~chr21:38975000-39000000,
chr21:38800000-38825000~~chr21:38975000-39000000,
chr21:38800000-38825000~~chr21:39000000-39025000,
chr21:38900000-38925000~~chr21:39000000-39025000,
chr21:38909314-38910891~~chr21:38992131-38994558,
chr21:38992131-38994558~~chr21:39065920-39068738,
chr21:39000000-39025000~~chr21:39150000-39175000,
chr21:39000000-39025000~~chr21:39375000-39400000,
chr21:39000000-39025000~~chr21:39425000-39450000,