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Basic information

CohesinDB ID: CDBP00419366

Locus: chr21-39024973-39026738

Data sourse: GSE67783, GSE86191, GSE98367, GSE206145-NatGen2015, ENCSR153HNT

Cell type: Fibroblast, HCT-116, K-562, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 52%, "9_Het": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TRIM25, CBFA2T2, POU2F2, BRD1, FOSL1, MYCN, PGR, TOP2A, ZFX, XBP1, ZBTB48, WT1, MYC, SP140, ZNF48, SMAD4, FOS, NR3C1, TRIM28, NR2F1, SNAI2, STAG1, ESR1, SETDB1, TBX5, AR, HSF1, ZBTB26, MAZ, ETV5

Target gene symbol (double-evidenced CRMs): ERG,GET1,ETS2,GET1-SH3BGR,PSMG1,SH3BGR,LCA5L

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 15

Related genes and loops

Related gene: ENSG00000157554, ENSG00000157557, ENSG00000183527, ENSG00000285815, ENSG00000182093, ENSG00000157578, ENSG00000185437,

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Deatailed information for cohesin site CDBP00419366