- Basic information
- CohesinDB ID: CDBP00419367
- Locus: chr21-39027861-39028086
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Data sourse: GSE110061, GSE108869
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Cell type: HeLa-S3, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 42%,
"9_Het": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, SOX2, XBP1, SUZ12, RING1B, TFAP4, ATF3, NFIC, ZC3H8, CHD7, DPF1, SMARCE1, ZNF287, TEAD1, TRIM28, ETV1, ZNF217, ESR1, OCA2, PITX3, USF2, CTCF, TCF12, ZNF507, EP300, MNT, GATA6, DPF2, RYBP, E2F6, RAD51, ZNF280A, TEAD4, GTF2F1, PDX1, TFAP2C, NANOG, BRD1, ZSCAN5D, MYCN, POU5F1, CTBP1, ZBTB17, ZBTB48, ZSCAN5A, STAT1, SP4, ERG, MYC, RAD21, RXRA, GABPA, STAT3, RCOR1, NR2F6, NR3C1, CEBPB, CREB1, GRHL2, EBF3, HDAC2, GATA2, GATAD2B, FLI1, SREBF1, NCOA2, ETV5, CBX1, CEBPA, SIN3A, ZFX, SMAD3, TWIST1, SMARCC1, CREBBP, RARA, SMAD2, GATA4, PBX4, SOX11, ATF2, SMAD4, PBX3, FOXM1, MED1, TEAD3, ZEB1, ZMYM3, NR1H2, SETDB1, TBX5, USF1, SP1, TFAP2A, HNF4A, NKX2-5, REST, ZNF479, ZBTB7A, RBM25, ASH2L, CTBP2, BCOR, SMC3, STAG1, MLLT1, FOXA2, RBBP5, CHD2, SS18, MIER2, WT1, KDM1A, YY1, RELA, ISL1, SP140, ZFP36, HIF1A, PCGF1, TCF4, MCM3, GATA3, MAX, NRIP1, GATA1, ZNF143, MTA1, HAND2, NR2F2, NR2F1, TP53, PKNOX1, ZNF687, ZFP28, AR, TAF1, ZNF579, YAP1, EGR1, BRD4, JUND, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): ETS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000157557,
- Related loop:
chr21:38450000-38475000~~chr21:39000000-39025000,
chr21:38575000-38600000~~chr21:39000000-39025000,
chr21:38650000-38675000~~chr21:39000000-39025000,
chr21:38733115-38735253~~chr21:39022229-39023588,
chr21:38733127-38735189~~chr21:39020330-39024316,
chr21:38733295-38735171~~chr21:39022214-39024026,
chr21:38800000-38825000~~chr21:39000000-39025000,
chr21:38800000-38825000~~chr21:39025000-39050000,
chr21:38804148-38807306~~chr21:39022163-39023870,
chr21:38804397-38807388~~chr21:39020330-39024316,
chr21:38830488-38833913~~chr21:39020753-39024286,
chr21:38875000-38900000~~chr21:39025000-39050000,
chr21:38900000-38925000~~chr21:39000000-39025000,
chr21:38900000-38925000~~chr21:39025000-39050000,
chr21:38925000-38950000~~chr21:39025000-39050000,
chr21:39000000-39025000~~chr21:39150000-39175000,
chr21:39000000-39025000~~chr21:39375000-39400000,
chr21:39000000-39025000~~chr21:39425000-39450000,
chr21:39020753-39024286~~chr21:39046917-39049378,