- Basic information
- CohesinDB ID: CDBP00419369
- Locus: chr21-39031159-39032411
-
Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, GSE86191
-
Cell type: RPE, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 46%,
"5_TxWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, PGR, SOX2, XBP1, SUZ12, RING1B, TFAP4, ATF3, NFIC, ZC3H8, CHD7, DPF1, SMARCE1, ZNF287, TEAD1, TRIM28, ETV1, ZNF217, ESR1, OCA2, PITX3, USF2, CTCF, TCF12, ZNF507, EP300, MNT, GATA6, DPF2, RYBP, E2F6, RAD51, ZNF280A, TEAD4, GTF2F1, PDX1, TFAP2C, NANOG, BRD1, ZSCAN5D, MYCN, POU5F1, CTBP1, ZBTB17, ZBTB48, ZSCAN5A, STAT1, SP4, ERG, MYC, RAD21, RXRA, GABPA, STAT3, RCOR1, NR2F6, NR3C1, CEBPB, CREB1, GRHL2, EBF3, HDAC2, GATA2, GATAD2B, FLI1, SREBF1, NCOA2, ETV5, CBX1, CEBPA, SIN3A, ZFX, SMAD3, TWIST1, SMARCC1, CREBBP, RARA, SMAD2, GATA4, PBX4, SOX11, ATF2, SMAD4, PBX3, FOXM1, MED1, TEAD3, ZEB1, ZMYM3, NR1H2, SETDB1, TBX5, USF1, SP1, TFAP2A, HNF4A, NKX2-5, REST, ZNF479, ZBTB7A, RBM25, ASH2L, CTBP2, BCOR, SMC3, STAG1, MLLT1, FOXA2, RBBP5, CHD2, SS18, MIER2, WT1, KDM1A, YY1, RELA, ISL1, SP140, ZFP36, HIF1A, PCGF1, TCF4, MCM3, GATA3, MAX, NRIP1, GATA1, ZNF143, MTA1, HAND2, NR2F2, NR2F1, TP53, PKNOX1, ZNF687, ZFP28, AR, TAF1, ZNF579, YAP1, EGR1, BRD4, JUND, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): ETS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 9
- Related genes and loops