- Basic information
- CohesinDB ID: CDBP00419373
- Locus: chr21-39040336-39041026
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Data sourse: GSE101921, GSE73207, ENCSR230ZWH, ENCSR917QNE
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Cell type: Liver, TF-1, HCAEC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SMC3,Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 55%,
"7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, ZSCAN5C, MEIS1, ERF, STAT1, CBX8, ERG, YY1, RELA, ZNF492, LYL1, JUNB, ETS1, ONECUT1, RAD21, RXRA, GATA3, HMGB2, GABPA, MECOM, TAL1, MAX, FOS, CDK8, PDX1, NR2F2, TRIM28, MYB, ELF1, LMO2, EVI1, CTCF, TCF12, JUN, SPI1, SP1, BCL11A, HNF4A, NR4A1, GATA2, EGR1, FLI1, HSF1, ZBTB26, BRD4, SCRT1, SMC1, SMC3, STAG2, AHR
- Target gene symbol (double-evidenced CRMs): ETS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 8
- Related genes and loops