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Basic information

CohesinDB ID: CDBP00419376

Locus: chr21-39045369-39046036

Data sourse: GSE206145-NatGen2015, GSE94872, GSE67783, GSE86191

Cell type: HUVEC, Fibroblast, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 71%, "5_TxWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, CHD8, ZSCAN5D, MYCN, TOP2A, RUNX1T1, ZFX, NME2, DUX4, ZBTB48, WT1, ZSCAN5A, STAT1, FOXA1, HOXB13, YY1, RELA, CREBBP, ZNF384, ASCL1, JUNB, ETS1, MYC, RAD21, SP140, GRHL3, HIF1A, GABPA, STAT3, TAL1, TP63, ZNF143, FOS, GATA1, ZNF736, TEAD3, ZNF573, ESR1, OCA2, ZNF334, CTCF, JUN, SPI1, BAF155, AR, GATA2, HEXIM1, HSF1, NOTCH3, SCRT1, SMC1, SMC3, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): ETS2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000157557,

eachgene

Deatailed information for cohesin site CDBP00419376