- Basic information
- CohesinDB ID: CDBP00419382
- Locus: chr21-39054530-39055364
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Data sourse: GSE206145-GSE177045, GSE67783, GSE98367
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Cell type: MCF-7, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 46%,
"5_TxWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, ZBTB40, POU2F2, GATA2, MYB, PIAS1, ARNT, HIF1A, ESR1, GRHL2, FOXA1, MEF2C, ZNF189, SP2, CDK8
- Target gene symbol (double-evidenced CRMs): ETS2,ERG
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000157554,
ENSG00000157557,
- Related loop:
chr21:38525000-38550000~~chr21:39050000-39075000,
chr21:38700000-38725000~~chr21:39050000-39075000,
chr21:38800000-38825000~~chr21:39025000-39050000,
chr21:38800000-38825000~~chr21:39050000-39075000,
chr21:38850000-38875000~~chr21:39050000-39075000,
chr21:38875000-38900000~~chr21:39025000-39050000,
chr21:38875000-38900000~~chr21:39050000-39075000,
chr21:38900000-38925000~~chr21:39025000-39050000,
chr21:38900000-38925000~~chr21:39050000-39075000,
chr21:38925000-38950000~~chr21:39025000-39050000,
chr21:38925000-38950000~~chr21:39050000-39075000,
chr21:38950000-38975000~~chr21:39050000-39075000,