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Basic information

CohesinDB ID: CDBP00419386

Locus: chr21-39065855-39066363

Data sourse: GSE206145-GSE177045

Cell type: MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 72%, "14_ReprPCWk": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, XBP1, FOXA1, ATF3, PRDM1, PAX5, TEAD1, TRIM28, LMO2, ESR1, OCA2, JUN, CTCF, BAF155, GATA6, SOX5, PAX8, TRIM24, SOX6, ZNF528, SMC1, ZNF280A, ZNF92, EED, GLIS1, POU2F2, CHD8, ZSCAN5D, POU5F1, MYCN, CTBP1, ZBTB48, MLLT3, ERG, ETS1, MYC, RAD21, GRHL3, NKX3-1, IKZF1, RCOR1, HNRNPH1, NR2F6, NR3C1, CREB1, EZH2, BMPR1A, GRHL2, TRPS1, HDAC2, GATA2, ZNF554, RUNX1, BCL6, SMC1A, SOX13, ZFX, SIN3A, POU4F2, CREBBP, ZNF35, NOTCH1, RUNX2, CDK6, GATA4, ARNT, HMGB2, FOS, CDK8, MYB, PIAS1, ZNF331, SMAD1, C11orf30, SETDB1, EVI1, USF1, BCL11A, ZNF479, POU2F3, ZNF605, CTBP2, FOXP1, SMC3, STAG1, STAG2, TRP47, PPARG, FOXA2, ZSCAN16, WT1, HOXB13, KDM1A, YY1, RELA, JUNB, NEUROD1, SP140, HIF1A, OTX2, GATA3, TAL1, MAX, ZNF449, ZNF143, GATA1, CBX2, TLE3, ZFP69B, NCOA3, NR2F2, GFI1B, NR2F1, TCF7L2, KDM5B, T, AR, EGLN2, HSF1, RNF2, NOTCH3, BRD4, JUND, SCRT1, ZNF316

Target gene symbol (double-evidenced CRMs): ERG,ETS2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000157554, ENSG00000157557,

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Deatailed information for cohesin site CDBP00419386