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Basic information

CohesinDB ID: CDBP00419388

Locus: chr21-39071535-39072229

Data sourse: ENCSR000BTQ, ENCSR167MTG, ENCSR338DUC, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE165895, ENCSR000BLS, GSE206145, GSE206145-NatGen2015, ENCSR054FKH, GSE73207, ENCSR703TNG, GSE25021, ENCSR000EDW, ENCSR917QNE

Cell type: MCF-7, RPE, Fibroblast, Hep-G2, TF-1, Liver, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 7% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 55%, "7_Enh": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, HMG20A, XBP1, FOXA1, HLF, RXRB, ZFHX2, KDM3A, TFAP4, ATF3, NFIC, CHD7, WDHD1, SMARCE1, TEAD1, RCOR2, ESR1, CTCF, JUN, EP300, MNT, GATA6, SOX5, DPF2, DMAP1, RFX5, TEAD4, FOXA3, ZNF175, GATAD2A, RBPJ, TFAP2C, POU2F2, ZBTB48, GATAD1, SAP130, ARID3A, ERG2, ERG, MYC, EOMES, HOMEZ, RAD21, GRHL3, RXRA, NKX2-1, STAT3, ZNF614, XRCC5, MIER3, RCOR1, NR2F6, NR3C1, ESRRA, CEBPB, CREB1, EZH2, GRHL2, GABPB1, ZHX2, MIXL1, TFE3, IRF1, HDAC2, GATA2, ZNF644, ZGPAT, MXI1, NFIL3, ETV5, THAP11, SMC1A, BCL6, CBX1, CEBPA, SOX13, SIN3A, SMAD3, ERG3, SP5, SMARCC1, ZXDC, RARA, CREBBP, RUNX2, GATA4, NRF1, ARNT, SMAD4, FOXM1, MED1, TEAD3, PIAS1, ZMYM3, NCOA1, SP1, BCL11A, TFAP2A, HNF4A, IKZF5, REST, ASH2L, HNRNPLL, MBD2, FOXP1, HMGB1, STAG1, SKI, PPARG, FOXA2, CREM, MIER2, ZNF30, MAFF, ZNF574, TCF7, HOXB13, ZNF580, KDM1A, YY1, RELA, HIF1A, GATA3, MAX, GATA1, ZNF143, CEBPG, NR2F2, TP53, ELF3, KAT8, NFKBIZ, AR, ARID4B, YAP1, EGR1, ZBTB26, BRD4, JUND, ZNF24, ZFP42, AHR

Target gene symbol (double-evidenced CRMs): ERG,ETS2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000157554, ENSG00000157557,

eachgene

Deatailed information for cohesin site CDBP00419388