Browse_each

Basic information

CohesinDB ID: CDBP00419389

Locus: chr21-39077469-39078690

Data sourse: GSE111537, GSE98367, GSE120943, GSE165895

Cell type: OCI-AML-3, Monocytes, Macrophage, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 58%, "14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, PGR, HMG20A, XBP1, FOXA1, HLF, RXRB, ZFHX2, KDM3A, TFAP4, TSC22D4, LYL1, ATF3, CHD7, PRDM1, MECOM, PAX5, JMJD1C, TEAD1, TRIM28, ELF1, LMO2, ESR1, MLL, RCOR2, CTCF, TCF12, EP300, SOX5, E2F6, DMAP1, TRIM24, IRF4, E2F4, KMT2B, FOXA3, ZNF175, GATAD2A, TFAP2C, RBPJ, CHD8, ZSCAN5D, POU5F1, MYCN, TOP2A, ZBTB48, STAT1, GATAD1, SAP130, ERG2, HNF4G, ERG, ETS1, MYC, ONECUT1, SMARCA4, HOMEZ, RAD21, GRHL3, RXRA, GABPA, STAT3, XRCC5, ZNF614, RCOR1, NFE2, NR2F6, MIER3, VDR, ZNF750, CEBPB, NR3C1, KMT2A, CREB1, EZH2, ZNF652, GABPB1, ZHX2, SPI1, TFE3, MIXL1, IRF1, HDAC2, GATA2, INTS13, ZNF644, FLI1, DRAP1, ZGPAT, NFIL3, ATF1, PTBP1, ETV5, RUNX1, THAP11, SMC1A, BCL6, CEBPA, CBX1, SOX13, ZFX, PCBP2, TET2, CBX8, ERG3, SP5, RARA, PRPF4, CDK6, ARNT, SMAD4, FOS, CDK8, MED1, TEAD3, CEBPD, MYB, PIAS1, ZMYM3, MBD1, STAT5A, SP1, BCL11A, HNF4A, IKZF5, REST, RBM25, ASH2L, BCOR, TCF3, FOXP1, SMC3, MLLT1, STAG1, SKI, CBFA2T2, PPARG, FOXA2, CREM, MIER2, ZSCAN16, WT1, MEF2C, ZBTB33, CDK9, HOXB13, ZNF580, KDM1A, YY1, RELA, SP140, ZFP36, TCF4, HIF1A, BHLHE22, TAL1, MAX, ZNF143, CEBPG, NR2F2, NR2F1, KDM5B, ZBTB6, EGR2, ELF3, PHF5A, KAT8, NFKBIZ, AR, ARID4B, RXR, EGR1, HSF1, NCOR1, ZBTB26, BRD4, SCRT1, JUND, MAZ, AHR

Target gene symbol (double-evidenced CRMs): ETS2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000157557,

eachgene

Deatailed information for cohesin site CDBP00419389