- Basic information
- CohesinDB ID: CDBP00419393
- Locus: chr21-39091863-39092124
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Data sourse: GSE206145-NatGen2015, GSE67783, GSE38411
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Cell type: BCBL-1, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 57%,
"5_TxWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, PGR, HMG20A, SUZ12, RXRB, UBTF, KDM3A, ATF3, NFIC, ZFP64, THAP1, MXD4, ZNF189, ZNF506, TEAD1, TRIM28, RBM39, SNAI2, NFE2L2, RCOR2, ESR1, JUN, CTCF, EP300, SOX5, PAX8, E2F1, SMC1, FOXA3, GATAD2A, RBPJ, TFAP2C, ZSCAN5D, MYCN, ZNF263, CTBP1, ZBTB48, STAT1, GATAD1, SAP130, ERG, MYC, HOMEZ, RAD21, STAT3, XRCC5, UBN1, ZNF614, IKZF1, MIER3, RCOR1, ZNF639, NR2F6, NR3C1, CEBPB, CREB1, CCAR2, ZNF652, GABPB1, ZHX2, SPI1, MIXL1, EHF, GATA2, ZNF644, MXD3, DRAP1, ZGPAT, NFIL3, ZNF554, ETV5, BCL6, SMC1A, CEBPA, CBX1, SOX13, ZFX, ZNF770, CBX8, SP5, RARA, NFYC, ZBTB2, RUNX2, ZNF184, PBX4, DAXX, TFDP1, ZNF48, SMAD4, FOS, CDK8, HMGXB4, TEAD3, ZMYM3, ZNF3, L3MBTL2, MAFK, NIPBL, HNF4A, IKZF5, REST, ZNF548, SMC3, STAG2, STAG1, MLLT1, NFATC3, SKI, PPARG, FOXA2, MTA3, MIER2, WT1, MEF2C, ZNF580, KDM1A, RELA, JUNB, NEUROD1, MCM3, SP140, ZFP36, HIF1A, SKIL, GATA3, TAL1, MAX, NRIP1, ZNF143, GATA1, CEBPG, NR2F1, KDM5B, TP53, ELF3, ARID4B, AR, BHLHE40, NFKBIZ, RB1, ZBTB26, HSF1, NCOR1, JUND, BRD4, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): ETS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000157557,
- Related loop:
chr21:17425000-17450000~~chr21:39075000-39100000,
chr21:38732732-38735278~~chr21:39086152-39087364,
chr21:38732774-38735251~~chr21:39086169-39087327,
chr21:38732867-38735207~~chr21:39088403-39089864,
chr21:38732918-38735320~~chr21:39086131-39087401,
chr21:38733392-38735200~~chr21:39086157-39087349,
chr21:38800000-38825000~~chr21:39075000-39100000,
chr21:38804148-38807306~~chr21:39086131-39087401,
chr21:38804598-38805801~~chr21:39086120-39087303,
chr21:38900000-38925000~~chr21:39075000-39100000,