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Basic information

CohesinDB ID: CDBP00419398

Locus: chr21-39113959-39114286

Data sourse: GSE206145

Cell type: RPE

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 66%, "5_TxWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, ZNF496, SOX2, MEIS2, XBP1, FOXA1, PBX2, ZNF90, ATF3, NFIC, ZFP64, MECOM, TEAD1, NFE2L2, LMO2, ESR1, OCA2, TP73, HDAC8, JUN, TCF12, CTCF, EP300, DPF2, SOX4, E2F1, TEAD4, PDX1, TFAP2C, GLIS1, CHD8, BRD1, MYCN, ZNF263, TOP2A, ZBTB48, STAT1, SRF, ARID3A, TBP, HOXC5, ERG, MYC, SMARCA4, ARID1B, RAD21, RXRA, STAT3, ZNF614, XRCC5, IKZF1, NFE2, RCOR1, VDR, NR3C1, CEBPB, CREB1, EBF3, ZHX2, SPI1, GATA2, MXI1, MRTFB, ETV5, RUNX1, SMC1A, MAFG, CEBPA, SOX13, ZFX, SMAD3, TET2, ERG3, SP5, TWIST1, SMARCC1, PRDM10, ZNF384, RUNX2, PBX4, DAXX, NRF1, ATF2, SMAD4, CBFA2T3, PBX3, FOS, CDK8, MED1, TEAD3, CEBPD, SMAD1, SUPT16H, C11orf30, SREBF2, MAFK, BCL11A, ZBTB7A, ZNF479, CTBP2, BCOR, SMC3, STAG1, FOXA2, TBL1X, CBX3, MEIS1, SS18, ZNF600, WT1, MEF2C, ZBTB33, KDM1A, YY1, RELA, JUNB, SP140, ZIC2, GATA3, TAL1, MAX, GATA1, ZNF143, HAND2, CEBPG, NCOA3, GFI1B, KDM5B, TP53, PKNOX1, BRD2, T, AR, YAP1, HSF1, RNF2, ZBTB26, JUND, BRD4, MAZ, TBX2, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): ERG,ETS2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000157554, ENSG00000157557,

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Deatailed information for cohesin site CDBP00419398