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Basic information

CohesinDB ID: CDBP00419400

Locus: chr21-39116710-39117795

Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, GSE165895

Cell type: RPE, Fibroblast, HCT-116, HSPC, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 67%, "14_ReprPCWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, JARID2, TRP47, POU2F2, CHD8, ZNF316, BRD1, MYCN, POU5F1, SIRT6, ZSCAN5D, ZFX, WT1, ZBTB48, ZSCAN5A, TET2, ERG3, ZFHX2, YY1, RELA, TARDBP, OGG1, ATF3, MYC, SP140, GRHL3, HIF1A, ATF4, STAT3, GATA1, RCOR1, DNMT3B, CEBPG, CEBPB, ZNF750, SRSF3, KLF4, TRIM28, RBM39, NR2F1, EZH2, STAG1, ESR1, OCA2, GRHL2, ZNF334, EGR2, CTCF, JUN, KLF1, AR, EGR1, HSF1, MAZ, AATF, SMC3, ZNF24, ETV5, AHR

Target gene symbol (double-evidenced CRMs): ERG,ETS2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 9

Related genes and loops

Related gene: ENSG00000157554, ENSG00000157557,

eachgene

Deatailed information for cohesin site CDBP00419400