- Basic information
- CohesinDB ID: CDBP00419403
- Locus: chr21-39132355-39132622
-
Data sourse: ENCSR167MTG, GSE72082, ENCSR000BLS, ENCSR054FKH, GSE68388
-
Cell type: HuCC-T1, Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 82%,
"14_ReprPCWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, HMG20A, XBP1, FOXA1, RXRB, KDM3A, TFAP4, TSC22D4, THRB, NFIC, TEAD1, RCOR2, ESR1, OCA2, TP73, JUN, CTCF, EP300, SOX5, DMAP1, RFX5, TEAD4, FOXA3, ZNF175, GATAD2A, RBPJ, MLX, POU2F2, CHD8, TOP2A, KDM4C, ZSCAN5A, GATAD1, SAP130, MYC, HOMEZ, RXRA, PROX1, MCRS1, ZNF614, PRDM14, MIER3, NR2F6, NR3C1, CREB1, TBL1XR1, TFE3, MIXL1, HDAC2, GATA2, ZNF644, DRAP1, ZGPAT, NFIL3, NCOA2, ETV5, THAP11, BCL6, MAFG, CEBPA, SOX13, ZFX, SMAD3, SMARCC1, MYBL2, RARA, ZNF384, SMAD4, MED1, TEAD3, ZEB1, C11orf30, TBX5, ZNF22, MAFK, SP1, HNF4A, IKZF5, ASH2L, FOXP1, NCOR2, STAG1, SKI, PPARG, FOXA2, CREM, MIER2, MAFF, WT1, ESR2, TCF7, HOXB13, ZNF580, KDM1A, YY1, RELA, MAX, CEBPG, NR2F2, NEUROG2, TP53, ZNF334, ELF3, PHF5A, KAT8, NFKBIZ, ARID4B, AR, JUND, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): ERG,KCNJ6,ETS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000157542,
ENSG00000157554,
ENSG00000157557,
- Related loop:
chr21:36000000-36025000~~chr21:39125000-39150000,
chr21:36425000-36450000~~chr21:39125000-39150000,
chr21:37675000-37700000~~chr21:39125000-39150000,
chr21:37700000-37725000~~chr21:39125000-39150000,
chr21:38150000-38175000~~chr21:39125000-39150000,
chr21:38158472-38160305~~chr21:39136790-39139170,
chr21:38200000-38225000~~chr21:39125000-39150000,
chr21:38343298-38344481~~chr21:39136825-39139305,
chr21:38350000-38375000~~chr21:39125000-39150000,
chr21:38355442-38357264~~chr21:39135757-39139176,
chr21:38375000-38400000~~chr21:39125000-39150000,
chr21:38379963-38381222~~chr21:39137274-39139116,
chr21:38450000-38475000~~chr21:39125000-39150000,
chr21:38475000-38500000~~chr21:39125000-39150000,
chr21:38500000-38525000~~chr21:39125000-39150000,
chr21:38504651-38506971~~chr21:39137271-39139180,
chr21:38504659-38506970~~chr21:39135752-39139340,
chr21:38504661-38506972~~chr21:39135752-39139234,
chr21:38504693-38507356~~chr21:39135757-39139176,
chr21:38504694-38507025~~chr21:39135761-39139165,
chr21:38504699-38507035~~chr21:39136221-39139367,
chr21:38504701-38506502~~chr21:39135777-39139304,
chr21:38504704-38506958~~chr21:39135757-39139157,
chr21:38504708-38507639~~chr21:39135753-39139144,
chr21:38504709-38506958~~chr21:39136233-39139143,
chr21:38504715-38506948~~chr21:39125188-39128467,
chr21:38504715-38506948~~chr21:39136158-39139240,
chr21:38504715-38507432~~chr21:39137265-39139144,
chr21:38504722-38507046~~chr21:39135777-39139215,
chr21:38504723-38507444~~chr21:39135766-39139156,
chr21:38504725-38506920~~chr21:39136965-39139305,
chr21:38504729-38506966~~chr21:39136708-39139166,
chr21:38504735-38506980~~chr21:39135742-39136980,
chr21:38504738-38506474~~chr21:39137262-39139083,
chr21:38504739-38507562~~chr21:39137207-39139175,
chr21:38504745-38506938~~chr21:39136790-39139170,
chr21:38504783-38506832~~chr21:39135735-39136956,
chr21:38504783-38506832~~chr21:39137550-39139120,
chr21:38504824-38507757~~chr21:39135757-39139204,
chr21:38504928-38507061~~chr21:39135759-39139198,
chr21:38505033-38506464~~chr21:39136191-39139182,
chr21:38505044-38506990~~chr21:39135737-39136964,
chr21:38505086-38506468~~chr21:39136216-39139158,
chr21:38505153-38506875~~chr21:39135794-39136979,
chr21:38505153-38506875~~chr21:39137264-39139102,
chr21:38505190-38506606~~chr21:39136767-39139174,
chr21:38505221-38506513~~chr21:39137257-39139089,
chr21:38511147-38512755~~chr21:39136825-39139305,
chr21:38511187-38512681~~chr21:39136158-39139240,
chr21:38511190-38512744~~chr21:39135761-39139165,
chr21:38511252-38512555~~chr21:39135781-39139348,
chr21:38525000-38550000~~chr21:39125000-39150000,
chr21:38620685-38621928~~chr21:39137249-39139154,
chr21:38650000-38675000~~chr21:39125000-39150000,
chr21:38668369-38670536~~chr21:39135774-39139290,
chr21:38668432-38670423~~chr21:39135752-39139234,
chr21:38668443-38670408~~chr21:39135763-39136936,
chr21:38668443-38670408~~chr21:39136965-39139305,
chr21:38668473-38670334~~chr21:39136825-39139305,
chr21:38668492-38670300~~chr21:39137207-39139175,
chr21:38668589-38670460~~chr21:39137271-39139180,
chr21:38668612-38670314~~chr21:39135742-39136980,
chr21:38668618-38670577~~chr21:39135757-39139176,
chr21:38668646-38670341~~chr21:39135759-39139198,
chr21:38668658-38670293~~chr21:39135754-39136962,
chr21:38668658-38670293~~chr21:39137265-39139144,
chr21:38668670-38670341~~chr21:39135777-39139215,
chr21:38668681-38670318~~chr21:39136853-39139127,
chr21:38668690-38670119~~chr21:39137264-39139102,
chr21:38668700-38670270~~chr21:39135761-39139165,
chr21:38668723-38670034~~chr21:39137401-39139164,
chr21:38668743-38670427~~chr21:39135787-39137068,
chr21:38675000-38700000~~chr21:39125000-39150000,
chr21:38698410-38700041~~chr21:39136627-39139221,
chr21:38698689-38700039~~chr21:39136191-39139182,
chr21:38700000-38725000~~chr21:39125000-39150000,
chr21:38711369-38713335~~chr21:39135774-39139290,
chr21:38711393-38713353~~chr21:39135753-39139144,
chr21:38711664-38713198~~chr21:39136158-39139240,
chr21:38725000-38750000~~chr21:39125000-39150000,
chr21:38732441-38735255~~chr21:39134896-39136193,
chr21:38732441-38735255~~chr21:39136199-39139181,
chr21:38732695-38735241~~chr21:39125188-39128467,
chr21:38732695-38735241~~chr21:39136158-39139240,
chr21:38732707-38735284~~chr21:39125195-39128459,
chr21:38732707-38735284~~chr21:39136221-39139367,
chr21:38732732-38735278~~chr21:39135742-39136980,
chr21:38732732-38735278~~chr21:39137257-39139164,
chr21:38732755-38735268~~chr21:39127096-39128415,
chr21:38732755-38735268~~chr21:39135781-39139348,
chr21:38732774-38735251~~chr21:39136853-39139127,
chr21:38732781-38735273~~chr21:39135774-39139290,
chr21:38732867-38735207~~chr21:39135759-39139198,
chr21:38732878-38735149~~chr21:39135777-39139304,
chr21:38732907-38735171~~chr21:39125144-39128433,
chr21:38732907-38735171~~chr21:39136778-39139387,
chr21:38732910-38735120~~chr21:39136838-39139138,
chr21:38732911-38735131~~chr21:39136708-39139166,
chr21:38732912-38735244~~chr21:39135752-39139340,
chr21:38732913-38735227~~chr21:39136217-39139134,
chr21:38732918-38735320~~chr21:39135763-39136936,
chr21:38732918-38735320~~chr21:39136965-39139305,
chr21:38732922-38735240~~chr21:39135753-39139144,
chr21:38733038-38735171~~chr21:39137207-39139175,
chr21:38733040-38735256~~chr21:39136790-39139170,
chr21:38733058-38735154~~chr21:39136784-39139132,
chr21:38733090-38735078~~chr21:39135768-39139113,
chr21:38733095-38735102~~chr21:39137262-39139083,
chr21:38733109-38735129~~chr21:39136233-39139143,
chr21:38733112-38735280~~chr21:39125212-39128459,
chr21:38733112-38735280~~chr21:39136825-39139305,
chr21:38733113-38735237~~chr21:39135777-39139215,
chr21:38733115-38735253~~chr21:39135735-39136956,
chr21:38733115-38735253~~chr21:39137550-39139120,
chr21:38733115-38735333~~chr21:39135752-39139234,
chr21:38733120-38735170~~chr21:39136279-39139355,
chr21:38733127-38735189~~chr21:39136216-39139158,
chr21:38733139-38735257~~chr21:39136627-39139221,
chr21:38733149-38735103~~chr21:39137200-39139115,
chr21:38733149-38735253~~chr21:39135761-39139165,
chr21:38733167-38735225~~chr21:39136793-39139191,
chr21:38733294-38735138~~chr21:39135754-39136962,
chr21:38733295-38735171~~chr21:39125184-39128368,
chr21:38733295-38735171~~chr21:39135757-39136968,
chr21:38733299-38735274~~chr21:39135757-39139157,
chr21:38733311-38735294~~chr21:39135757-39139176,
chr21:38733315-38735206~~chr21:39136191-39139182,
chr21:38733333-38735287~~chr21:39127128-39128385,
chr21:38733333-38735287~~chr21:39135766-39139156,
chr21:38733337-38735102~~chr21:39135737-39136964,
chr21:38733337-38735102~~chr21:39137401-39139164,
chr21:38733340-38735147~~chr21:39135757-39139091,
chr21:38733341-38735220~~chr21:39135746-39136928,
chr21:38733341-38735220~~chr21:39137271-39139180,
chr21:38733359-38735265~~chr21:39136719-39139116,
chr21:38733366-38735207~~chr21:39137617-39139161,
chr21:38733385-38734881~~chr21:39137257-39139089,
chr21:38733386-38735279~~chr21:39137377-39139144,
chr21:38733387-38735224~~chr21:39137436-39139060,
chr21:38733388-38735159~~chr21:39137401-39139117,
chr21:38733388-38735372~~chr21:39137249-39139154,
chr21:38733389-38735343~~chr21:39135794-39136979,
chr21:38733389-38735343~~chr21:39137264-39139102,
chr21:38733392-38735130~~chr21:39137353-39139078,
chr21:38733392-38735200~~chr21:39137401-39139120,
chr21:38733416-38734790~~chr21:39136767-39139174,
chr21:38795738-38797863~~chr21:39135757-39139176,
chr21:38800000-38825000~~chr21:39125000-39150000,
chr21:38804025-38807695~~chr21:39135752-39139340,
chr21:38804026-38806194~~chr21:39135746-39136928,
chr21:38804026-38806194~~chr21:39137271-39139180,
chr21:38804033-38807696~~chr21:39136199-39139181,
chr21:38804038-38807501~~chr21:39135777-39139304,
chr21:38804047-38805972~~chr21:39125144-39128433,
chr21:38804079-38807181~~chr21:39125184-39128368,
chr21:38804079-38807181~~chr21:39137214-39139028,
chr21:38804103-38806461~~chr21:39135752-39139234,
chr21:38804112-38806553~~chr21:39136790-39139170,
chr21:38804130-38806749~~chr21:39135757-39139157,
chr21:38804148-38807306~~chr21:39135763-39136936,
chr21:38804148-38807306~~chr21:39136965-39139305,
chr21:38804213-38806093~~chr21:39135757-39139176,
chr21:38804263-38806143~~chr21:39135761-39139165,
chr21:38804397-38807388~~chr21:39136216-39139158,
chr21:38804450-38807728~~chr21:39136191-39139182,
chr21:38804482-38806565~~chr21:39136279-39139355,
chr21:38818748-38820756~~chr21:39136216-39139158,
chr21:38900000-38925000~~chr21:39125000-39150000,
chr21:38925000-38950000~~chr21:39125000-39150000,
chr21:38950000-38975000~~chr21:39125000-39150000,