Browse_each

Basic information

CohesinDB ID: CDBP00419407

Locus: chr21-39153009-39153827

Data sourse: ENCSR000BLD, GSE104888, ENCSR230ZWH, ENCSR000FAD, GSE72082, ENCSR000BSB, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE121355, GSE111537, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE165895, GSE143937, GSE93080, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE101921, GSE152721, GSE206145-NatGen2015, GSE112028, ENCSR703TNG, GSE116344, GSE145327, GSE94872, ENCSR000EEG, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, GSE55407, ENCSR000BTQ, ENCSR167MTG, GSE110061, GSE129526, ENCSR000HPG, GSE111913, GSE155324, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS

Cell type: RH4, GM19240, Liver, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, DKO, HFFc6, GM18526, H1-hESC, GM18505, Lymphoblast, GM12878, GM12891, GM2588, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, HAP1, GM19099, HUES64, MCF-7, GM12892, THP-1, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, A-549, HUVEC, HCAEC, GM19238, OCI-AML-3, GM18951

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 26% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.500

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 81%, "14_ReprPCWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: XBP1, FOXA1, PBX2, UBTF, CTCFL, ZNF444, ZNF121, TRIM28, SNAI2, NFE2L2, ESR1, OCA2, CTCF, E2F6, ZNF528, SMC1, TEAD4, TFAP2C, POU2F2, CHD8, BRD1, ZSCAN5D, MYCN, POU5F1, ZSCAN5A, STAT1, SRF, ERG, ASCL1, MYC, RAD21, RXRA, NKX2-1, XRCC5, NFE2, RCOR1, CREB1, CCAR2, EZH2, GRHL2, SPI1, ZNF554, RUNX1, MAFG, SMC1A, CBX1, ZFX, ZNF534, SMAD3, TRIM22, ZBTB2, ARNT, PBX4, SMARCB1, CDK8, FOS, HMGXB4, PIAS1, C11orf30, TBX5, MAFK, BCL11A, HNF4A, REST, TCF3, SMC3, STAG1, CBX3, FOXA2, WT1, MAFF, YY1, RELA, JUNB, ZFP36, HIF1A, TCF4, BHLHE22, NRIP1, ZNF143, GATA1, NCOA3, GFI1B, NR2F2, TP53, ZNF334, MYOD1, BRD2, AR, EGLN2, RB1, RNF2, SCRT1, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): SH3BGR,KCNJ6,LCA5L,GET1-SH3BGR,GET1,ERG

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554, ENSG00000285815, ENSG00000182093, ENSG00000157578, ENSG00000185437,

eachgene

Deatailed information for cohesin site CDBP00419407