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Basic information

CohesinDB ID: CDBP00419409

Locus: chr21-39156653-39158153

Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, GSE120943, ENCSR153HNT, ENCSR703TNG, GSE131606

Cell type: MCF-7, RPE, Fibroblast, HCT-116, Monocytes, K-562, HSPC, DKO

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.911

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 82%, "14_ReprPCWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: .

Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,GET1,ERG,KCNJ6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 7

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554, ENSG00000285815, ENSG00000182093,

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Deatailed information for cohesin site CDBP00419409