Browse_each

Basic information

CohesinDB ID: CDBP00419414

Locus: chr21-39173429-39176751

Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, ENCSR760NPX, ENCSR000BLY, ENCSR404BPV, ENCSR150EFU, GSE105028, GSE121355, GSE73207, GSE103477, GSE111537, GSE131606, ENCSR330ELC, GSE108869, GSE25021, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, GSE165895, GSE93080, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE101921, ENCSR806UKK, GSE135093, GSE152721, ENCSR198ZYJ, GSE206145-NatGen2015, GSE112028, GSE130135, ENCSR199XBQ, ENCSR703TNG, GSE116344, GSE138105, GSE94872, ENCSR895JMI, ENCSR338DUC, ENCSR193NSH, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR247LSH, ENCSR807WAC, ENCSR000EHX, ENCSR620NWG, ENCSR767DFK, ENCSR981FDC, ENCSR495WGO, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE110061, GSE129526, ENCSR000HPG, ENCSR676MJK, GSE111913, GSE155324, ENCSR335RKQ, ENCSR537EFT, ENCSR000EDE, ENCSR153HNT, GSE83726, GSE126990, GSE50893, GSE126755, ENCSR748MVX, GSE131577

Cell type: MDM, RH4, GM10847, GM2610, SLK, GM19240, OCI-AML-3, HSPC, Liver, H9-hESC, RPE, GM2630, HMEC, Fibroblast, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, DKO, HFFc6, GM18526, H1-hESC, SNYDER, GM18505, Lymphoblast, TF-1, GM12878, GM12891, GM2588, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, GM19099, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, Neurons-H1, A-549, HUVEC, HCAEC, GM19238, HeLa, Neutrophil, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 45% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.400

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 47%, "4_Tx": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF391, ZSCAN5C, NME2, MEIS2, XBP1, PATZ1, FOXA1, RBFOX2, LEO1, PBX2, HDGF, LYL1, INSM2, ZBTB44, PRDM1, IKZF3, KLF14, MORC2, MECOM, ZNF189, TP63, MITF, ZNF467, ZNF629, TEAD1, BCLAF1, TRIM28, ZNF121, SNAI2, KLF10, LMO2, ESR1, OCA2, ZNF561, CTCF, TCF12, JUN, ZNF577, KLF1, GATA6, PRDM4, ZNF528, SMC1, TEAD4, PDX1, TFAP2C, EED, GLIS1, POU2F2, CHD8, NANOG, ZSCAN5D, MYCN, ZNF263, TOP2A, POU5F1, ZSCAN21, ZBTB17, ZBTB48, ZSCAN5A, STAT1, ZNF317, ZBTB1, SRF, DUX4, ARID3A, ERG, ZBTB8A, ZNF341, EZH1, MYC, EOMES, SMARCA4, ZNF2, RAD21, FOXP2, GRHL3, TSHZ1, ARID1B, FOXK2, DNMT3B, ZNF639, CEBPB, KLF8, FEZF1, EBF3, SPI1, ZNF664, KLF17, GATA2, ZNF146, FLI1, ZNF777, ZNF766, HEXIM1-CDK9, ZNF554, RUNX1, SMC1A, CEBPA, LDB1, NKX2-2, ZFX, ZNF654, ZNF770, TRIM22, ZNF18, SMARCC1, ZBTB2, ZNF35, RUNX2, GATA4, OSR2, ZNF184, ARNT, PBX4, ZEB2, ETV6, CBFA2T3, MAFB, SUPT5H, CDK8, SNRNP70, FOS, ZNF10, MED1, PML, CEBPD, ZXDB, SCRT2, PIAS1, ZNF3, EVI1, RBM22, MAFK, BCL11A, SP1, ARID2, OVOL3, GLI2, POU2F3, ZNF548, PHIP, TCF3, FOXP1, PRDM6, SMC3, ZNF34, STAG1, STAG2, ZNF394, CBFA2T2, TBL1X, FOXA2, PAF1, E2F8, ZNF600, ZNF692, SS18, WT1, ZSCAN16, ZNF574, ZBTB33, CDK9, ZKSCAN1, KDM1A, YY1, RELA, ZNF19, NEUROD1, SP140, HIF1A, OTX2, GATA3, TAL1, NRIP1, ZNF143, AGO2, GATA1, SP7, NCOA3, NR2F2, GFI1B, NR2F1, TP53, ZNF213, MYOD1, ZNF843, AR, ZNF579, ZNF324, ZNF366, ZBTB42, MYNN, NCOR1, NOTCH3, BRD4, ILF3, ZBTB26, SCRT1, MAZ, ZSCAN23, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): ETS2,KCNJ6,PSMG1,GET1-SH3BGR,LCA5L,ERG,HMGN1,SH3BGR,GET1,B3GALT5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 27

Number of somatic mutations (non-coding): 21

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554, ENSG00000157557, ENSG00000183527, ENSG00000205581, ENSG00000285815, ENSG00000182093, ENSG00000157578, ENSG00000185437, ENSG00000183778,

eachgene

Deatailed information for cohesin site CDBP00419414