Browse_each

Basic information

CohesinDB ID: CDBP00419418

Locus: chr21-39189884-39190456

Data sourse: GSE165895

Cell type: HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 77%, "7_Enh": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, MEF2B, FOXA2, NKX2-2, ZSCAN5C, TOP2A, PAF1, SOX2, NFATC1, XBP1, ZBTB17, ZBTB48, SMAD3, FOXA1, TCF7, CDK9, HOXB13, ERG, KDM1A, RELA, JUNB, AHR, MYC, RUNX2, ZNF184, RUNX3, PRDM1, GRHL3, ARNT, PBX4, PROX1, NKX2-1, ATF4, BATF3, ATF2, BATF, STAT3, MAX, SUPT5H, AGO2, FOS, GATA1, MED1, NR3C1, MAF, CEBPB, NCOA3, TERF1, CEBPG, KMT2A, MYB, ESR1, OCA2, GRHL2, EGR2, JUN, RBM22, USF1, SPI1, CTCF, AR, GATA6, GATA2, ATF7, BRD4, PHIP, JUND, FOXP1, PRDM6, TFAP2C

Target gene symbol (double-evidenced CRMs): HMGN1,BRWD1,B3GALT5,KCNJ6,ERG,SH3BGR,GET1,LCA5L,GET1-SH3BGR,ETS2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 12

Number of somatic mutations (non-coding): 7

Related genes and loops

Related gene: ENSG00000157542, ENSG00000157554, ENSG00000157557, ENSG00000185658, ENSG00000205581, ENSG00000285815, ENSG00000182093, ENSG00000157578, ENSG00000185437, ENSG00000183778,

eachgene

Deatailed information for cohesin site CDBP00419418