- Basic information
- CohesinDB ID: CDBP00419424
- Locus: chr21-39215761-39216148
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Data sourse: GSE206145-GSE177045, GSE67783
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Cell type: MCF-7, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 53%,
"5_TxWk": 47%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CHD8, MAFG, PAF1, ZFX, ZSCAN16, ZBTB48, WT1, MAFF, FOXA1, ERG3, NBN, ERG2, HOXB13, RELA, ZNF384, ZNF184, PRDM1, GRHL3, SP140, GATA3, PRDM9, GABPA, GLYR1, SUPT5H, GATA1, MED1, ZFP69B, TEAD1, SNAI2, ESR1, C11orf30, RBM22, MAFK, BCL11A, TFAP2A, AR, GATA2, SIX2, NCOR1, HOXA9, NOTCH3, BRD4, SCRT1, E2F1, HEXIM1-CDK9, PRDM6, ZZZ3, ZNF316
- Target gene symbol (double-evidenced CRMs): LCA5L,GET1,GET1-SH3BGR,SH3BGR,B3GALT5,BRWD1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
ENSG00000185437,
ENSG00000183778,
- Related loop:
chr21:39200000-39225000~~chr21:39300000-39325000,
chr21:39200000-39225000~~chr21:39375000-39400000,
chr21:39200000-39225000~~chr21:39400000-39425000,
chr21:39200000-39225000~~chr21:39425000-39450000,
chr21:39200000-39225000~~chr21:39600000-39625000,