- Basic information
- CohesinDB ID: CDBP00419425
- Locus: chr21-39219118-39219418
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Data sourse: GSE206145-NatGen2015, GSE206145-GSE177045, ENCSR153HNT
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Cell type: K-562, Fibroblast, MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 65%,
"4_Tx": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CHD8, POU5F1, PAF1, XBP1, GTF2B, FOXA1, ZNF205, ERG3, ERG2, NEUROD1, SMARCA4, ZNF610, PRDM1, ARNT, HIF1A, NKX2-1, GLYR1, PAX5, GATA1, SUPT5H, CEBPB, NCOA3, RBM22, AR, PAX8, KMT2B, ZZZ3, AHR
- Target gene symbol (double-evidenced CRMs): GET1,BRWD1,SH3BGR,B3GALT5,GET1-SH3BGR,LCA5L
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
ENSG00000185437,
ENSG00000183778,
- Related loop:
chr21:39200000-39225000~~chr21:39300000-39325000,
chr21:39200000-39225000~~chr21:39375000-39400000,
chr21:39200000-39225000~~chr21:39400000-39425000,
chr21:39200000-39225000~~chr21:39425000-39450000,
chr21:39200000-39225000~~chr21:39600000-39625000,