- Basic information
- CohesinDB ID: CDBP00419428
- Locus: chr21-39227967-39228342
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 56%,
"5_TxWk": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CHD8, TOP2A, PAF1, ZBTB48, FOXA1, ERG3, ERG2, HOXB13, ERG, ZNF384, NEUROD1, MYC, OTX2, GLYR1, STAT3, NKX3-1, SUPT5H, CDK8, TLE3, CEBPB, SP7, NCOA3, CREB1, PIAS1, COBLL1, SMAD5, FEZF1, PHOX2B, CTCF, NUP98-HOXA9, RBM22, BAF155, KLF1, AR, PAX3-FOXO1, GATA2, ARID1A, NCOR1, BRD4, ZZZ3, AHR
- Target gene symbol (double-evidenced CRMs): LCA5L,SH3BGR,GET1,GET1-SH3BGR,B3GALT5,BRWD1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
ENSG00000185437,
ENSG00000183778,
- Related loop:
chr21:39200000-39225000~~chr21:39300000-39325000,
chr21:39200000-39225000~~chr21:39375000-39400000,
chr21:39200000-39225000~~chr21:39400000-39425000,
chr21:39200000-39225000~~chr21:39425000-39450000,
chr21:39200000-39225000~~chr21:39600000-39625000,
chr21:39225000-39250000~~chr21:39375000-39400000,
chr21:39225000-39250000~~chr21:39400000-39425000,
chr21:39225000-39250000~~chr21:39425000-39450000,
chr21:39225000-39250000~~chr21:39600000-39625000,
chr21:39225000-39250000~~chr21:39700000-39725000,