- Basic information
- CohesinDB ID: CDBP00419431
- Locus: chr21-39235801-39236518
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 77%,
"5_TxWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, CHD8, SMC1A, TBL1X, MYCN, RUNX1T1, PAF1, ZFX, XBP1, ZBTB48, WT1, ZSCAN5A, LEO1, TBP, RELA, MYC, RUNX2, CDK6, SP140, ARNT, HIF1A, SOX11, HMBOX1, ZNF143, SUPT5H, DNMT3B, MED1, PLAG1, NR3C1, NCOA3, TEAD1, NR2F1, EZH2, ESR1, OCA2, NCOA1, CTCF, RBM22, SPI1, GSPT2, PAX3-FOXO1, AR, PAX8, ZBTB42, NOTCH3, BRD4, MAZ, SMC3, STAG1, EED
- Target gene symbol (double-evidenced CRMs): LCA5L,GET1,GET1-SH3BGR,BRWD1,B3GALT5,SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 27
- Number of somatic mutations (non-coding): 9
- Related genes and loops
- Related gene:
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
ENSG00000185437,
ENSG00000183778,
- Related loop:
chr21:39225000-39250000~~chr21:39375000-39400000,
chr21:39225000-39250000~~chr21:39400000-39425000,
chr21:39225000-39250000~~chr21:39425000-39450000,
chr21:39225000-39250000~~chr21:39600000-39625000,
chr21:39225000-39250000~~chr21:39700000-39725000,