- Basic information
- CohesinDB ID: CDBP00419444
- Locus: chr21-39281318-39282039
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Data sourse: GSE206145-GSE177045, GSE67783, GSE138405, GSE62063, ENCSR153HNT
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Cell type: MCF-7, Hela-Kyoto, K-562, HSPC, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 70%,
"4_Tx": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, NANOG, CHD8, ZNF316, TOP2A, SOX2, ZFX, PAF1, ZSCAN16, WT1, ZBTB48, ZSCAN5A, FOXA1, ZNF770, ZBTB33, CDK9, PBX2, HOXB13, SMARCC1, ERG, ZNF19, RELA, HDGF, ZNF384, JUNB, NEUROD1, MYC, GATA4, ZNF362, SMARCA4, PRDM1, ARNT, BACH1, OTX2, ZNF48, GLYR1, GABPA, STAT3, PAX5, NKX3-1, SUPT5H, CHD1, ZNF143, NFE2, MED1, TLE3, KLF4, ZNF121, CREB1, PIAS1, ESR1, PKNOX1, C11orf30, GRHL2, PHOX2B, CTCF, RBM22, BAF155, SPI1, ZNF664, AR, GATA2, ARID1A, EGLN2, ASH2L, BRD4, FOXP1, E2F1, PRDM6, MAZ, KMT2B, ZZZ3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): BRWD1,LCA5L,GET1-SH3BGR,GET1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 3
- Related genes and loops