- Basic information
- CohesinDB ID: CDBP00419446
- Locus: chr21-39295098-39295553
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Data sourse: GSE206145-NatGen2015, GSE206145-GSE177045, GSE67783, GSE86191
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Cell type: MCF-7, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 72%,
"5_TxWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, ZNF384, TRP47, MYC, PAF1, ARNT, ZMYND11, WT1, HOXA9, FOXA1, E2F1, GLYR1, ZZZ3, RBFOX2, CTCF, SUPT5H, SPI1, AHR
- Target gene symbol (double-evidenced CRMs): BRWD1,GET1,LCA5L,GET1-SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
- Related loop:
chr21:27500000-27525000~~chr21:39275000-39300000,
chr21:39200000-39225000~~chr21:39300000-39325000,
chr21:39275000-39300000~~chr21:39375000-39400000,
chr21:39275000-39300000~~chr21:39400000-39425000,
chr21:39300000-39325000~~chr21:39400000-39425000,
chr21:39300000-39325000~~chr21:39425000-39450000,
chr21:39300000-39325000~~chr21:39600000-39625000,
chr21:39300000-39325000~~chr21:39700000-39725000,