- Basic information
- CohesinDB ID: CDBP00419447
- Locus: chr21-39301995-39302301
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Data sourse: GSE206145-NatGen2015, GSE206145-GSE177045, GSE67783
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Cell type: MCF-7, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 63%,
"4_Tx": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NCOA2, FOXO1, FOSL1, CHD8, ZNF316, ZSCAN5D, MAFG, PAF1, ZFX, XBP1, GTF2B, MAFF, ZSCAN5A, ZBTB48, FOXA1, DUX4, ZBTB33, BAHD1, RBFOX2, LEO1, HOXB13, SFMBT1, ERG, CREBBP, ZNF384, NEUROD1, MYC, RUNX2, ZKSCAN2, RFX1, GRHL3, NKX2-1, GLYR1, ZNF189, PAX5, ZNF143, SUPT5H, MED1, NCOA3, PML, TRIM28, TP53, ZBTB6, C11orf30, NCOA1, ZNF334, SETDB1, ZNF22, CTCF, RBM22, MAFK, BCL11A, ZFP28, SPI1, AR, SOX5, PAX8, ZNF182, EGLN2, ZBTB42, ZBTB26, NOTCH3, BRD4, AFF1, ZNF567, ILF3, ZNF512B, ZNF528, ZNF280A, SMC3, AHR
- Target gene symbol (double-evidenced CRMs): B3GALT5,SH3BGR,BRWD1,LCA5L,GET1-SH3BGR,GET1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
ENSG00000185437,
ENSG00000183778,
- Related loop:
chr21:27500000-27525000~~chr21:39275000-39300000,
chr21:39200000-39225000~~chr21:39300000-39325000,
chr21:39275000-39300000~~chr21:39375000-39400000,
chr21:39275000-39300000~~chr21:39400000-39425000,
chr21:39300000-39325000~~chr21:39400000-39425000,
chr21:39300000-39325000~~chr21:39425000-39450000,
chr21:39300000-39325000~~chr21:39600000-39625000,
chr21:39300000-39325000~~chr21:39700000-39725000,