- Basic information
- CohesinDB ID: CDBP00419450
- Locus: chr21-39306051-39306835
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Data sourse: GSE206145-NatGen2015, GSE62063, GSE67783
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Cell type: Fibroblast, HSPC, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 87%,
"4_Tx": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF384, PAF1, SP140, RBFOX2, LEO1, SUPT5H
- Target gene symbol (double-evidenced CRMs): BRWD1,B3GALT5,LCA5L,GET1-SH3BGR,GET1,SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 24
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
ENSG00000185437,
ENSG00000183778,
- Related loop:
chr21:39200000-39225000~~chr21:39300000-39325000,
chr21:39300000-39325000~~chr21:39400000-39425000,
chr21:39300000-39325000~~chr21:39425000-39450000,
chr21:39300000-39325000~~chr21:39600000-39625000,
chr21:39300000-39325000~~chr21:39700000-39725000,
chr21:39311821-39314792~~chr21:39387238-39389498,