- Basic information
- CohesinDB ID: CDBP00419456
- Locus: chr21-39326856-39327201
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Data sourse: GSE105028, GSE67783, GSE86191, GSE206145
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Cell type: RPE, HCT-116, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 82%,
"14_ReprPCWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, NANOG, CHD8, POU2F2, POU5F1, MYCN, SOX2, ZFX, NME2, XBP1, WT1, ZBTB48, ZNF30, ZNF770, HOXB13, TBP, KDM1A, YY1, RELA, ZNF35, ASCL1, MYC, SMARCA4, THAP1, CHD7, MCM3, SP140, HIF1A, GRHL3, MAX, ETV6, ZNF143, FOS, RCOR1, ELF1, ZNF121, CREB1, NR2F1, U2AF1, EZH2, TP53, ESR1, NCOA1, MYOD1, CTCF, TCF12, PAX3-FOXO1, AR, ZBTB7A, ZBTB42, FLI1, HNRNPLL, BRD4, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): GET1,SH3BGR,ETS2,GET1-SH3BGR,LCA5L
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000157557,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
ENSG00000185437,
- Related loop:
chr21:38800000-38825000~~chr21:39325000-39350000,
chr21:39200000-39225000~~chr21:39300000-39325000,
chr21:39300000-39325000~~chr21:39400000-39425000,
chr21:39300000-39325000~~chr21:39425000-39450000,
chr21:39300000-39325000~~chr21:39600000-39625000,
chr21:39300000-39325000~~chr21:39700000-39725000,
chr21:39320997-39322719~~chr21:39347655-39350638,
chr21:39325000-39350000~~chr21:39425000-39450000,