- Basic information
- CohesinDB ID: CDBP00419458
- Locus: chr21-39329775-39330179
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Data sourse: GSE206145-GSE177045, GSE67783
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Cell type: MCF-7, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 88%,
"14_ReprPCWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF394, ZNF426, MEF2B, POU2F2, ZNF697, PGR, TOP2A, SIN3A, ZFX, ZNF534, ZBTB17, ZSCAN5A, ZNF101, FOXA1, DDX5, HOXB13, KDM1A, RELA, CREBBP, ZNF384, ZBTB8A, MYC, ZFP64, GR, PRDM1, GRHL3, HIF1A, ARNT, PRDM12, ZNF781, GATA3, PRDM9, ZNF518A, NFIB, TAL1, NKX2-1, TP63, NR3C1, TEAD1, ZBTB11, SCRT2, ZMYM3, EZH2, ESR1, TP53, HDAC8, ZNF22, ZNF577, CTCF, AR, REST, BRD4, SCRT1, ZNF528, ZNF623, ZNF555, ZNF34, AHR
- Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,LCA5L,ETS2,GET1,SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000157557,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
ENSG00000185437,
- Related loop:
chr21:38800000-38825000~~chr21:39325000-39350000,
chr21:39200000-39225000~~chr21:39300000-39325000,
chr21:39300000-39325000~~chr21:39400000-39425000,
chr21:39300000-39325000~~chr21:39425000-39450000,
chr21:39300000-39325000~~chr21:39600000-39625000,
chr21:39300000-39325000~~chr21:39700000-39725000,
chr21:39325000-39350000~~chr21:39425000-39450000,