- Basic information
- CohesinDB ID: CDBP00419460
- Locus: chr21-39332176-39332684
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR000FAD, GSE105028, ENCSR153HNT
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Cell type: K-562, H1-hESC, MCF-7, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 59%,
"5_TxWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, SOX2, XBP1, FOXA1, PBX2, RXRB, TFAP4, HDGF, CHD7, PRDM1, ZNF189, SMARCE1, PAX5, ZNF320, CDX2, TEAD1, NFE2L2, ESR1, OCA2, CTCF, TCF12, JUN, EP300, E4F1, GATA6, DPF2, SOX6, E2F1, GATAD2A, GLIS1, NANOG, ID3, CTBP1, MTA2, ZBTB48, SAP130, MYC, SMARCA4, EOMES, ARID1B, RAD21, GRHL3, FOXK2, STAT3, XRCC5, IKZF1, RCOR1, NR2F6, CEBPB, ESRRA, CREB1, ELF4, SPI1, HDAC2, GATA2, SMARCA5, NFIL3, ZNF554, ATF1, ETV5, BCL6, CEBPA, HDAC1, ZFX, SMAD3, ZNF770, RARA, CREBBP, SMAD2, GATA4, OSR2, ZEB2, SMAD4, ETV6, NR2C1, ZNF10, MED1, TEAD3, L3MBTL2, BCL11A, GSPT2, HNF4A, REST, ZBTB7A, MLLT1, MTA3, RBBP5, ZNF30, WT1, ZBTB33, ZNF580, KDM1A, YY1, RELA, JUNB, ZIC2, HIF1A, GATA3, MAX, NRIP1, GATA1, MTA1, ZNF143, HAND2, GFI1B, NCOA3, NR2F1, PKNOX1, MYOD1, T, BRD2, ELF3, PTRF, ZBTB40, ZBTB42, RNF2, BRD4, JUND, ILF3, MAZ
- Target gene symbol (double-evidenced CRMs): SH3BGR,LCA5L,GET1,GET1-SH3BGR,ETS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops