- Basic information
- CohesinDB ID: CDBP00419461
- Locus: chr21-39333291-39334572
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE67783, GSE72082, GSE86191, GSE132649, GSE76893, GSE206145-NatGen2015, ENCSR153HNT, ENCSR703TNG, GSE25021, GSE115602
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Cell type: MCF-7, T-47D, Fibroblast, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: Mau2,SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 68%,
"5_TxWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MBD3, PGR, CBX1, FOXA2, SIN3A, CTBP1, FOXA1, ZNF770, HOXB13, PRDM10, ERG, RELA, CREBBP, AHR, GATA4, OSR2, GR, RAD21, ARNT, HIF1A, GATA3, ZEB2, GABPA, SMARCE1, MAX, NKX3-1, ZNF143, MED1, TLE3, NR3C1, CEBPB, NR2F2, TEAD1, CREB1, NR2F1, TCF7L2, PIAS1, ZNF217, ESR1, ZBTB6, GRHL2, TRPS1, TCF12, EP300, TFAP2A, BCL11A, AR, DPF2, HDAC2, YAP1, GATA2, GATAD2B, EGLN2, HOXA9, CTBP2, BRD4, CLOCK, TEAD4, ZNF24, TFAP2C
- Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,ETS2,GET1,LCA5L,SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops