- Basic information
- CohesinDB ID: CDBP00419462
- Locus: chr21-39335104-39335948
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Data sourse: GSE206145-GSE177045, GSE67783, GSE206145, GSE206145-NatGen2015, ENCSR153HNT
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Cell type: MCF-7, RPE, Fibroblast, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 70%,
"5_TxWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: THAP11, NFIA, POU2F2, MEF2B, BCL6, SMC1A, POU5F1, ZNF600, XBP1, ZBTB48, WT1, GTF2F1, ZBTB33, SAP130, GATAD1, RXRB, HOXB13, KDM1A, ERG, RELA, ZBTB2, YY1, ASCL1, ZNF384, NEUROD1, MYC, HOMEZ, RAD21, GRHL3, OTX2, ZNF48, TAL1, XRCC5, ZNF614, ZNF143, CDK8, MITF, HMGXB4, ZNF736, DNMT3B, NR2F6, MIER3, NR3C1, SP7, TEAD3, NCOA3, TEAD1, KMT2A, CREB1, KLF6, TP73, MBD1, CTCF, PHF5A, ELF3, EP300, SPI1, NR4A1, ARID4B, ZNF644, ASH2L, ZBTB26, ZGPAT, BRD4, NFIL3, SMC3, GATAD2A, STAG1, ZNF316
- Target gene symbol (double-evidenced CRMs): SH3BGR,ETS2,GET1-SH3BGR,LCA5L,GET1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops