- Basic information
- CohesinDB ID: CDBP00419465
- Locus: chr21-39339920-39340238
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Data sourse: GSE206145-GSE177045, GSE86191
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Cell type: MCF-7, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 93%,
"15_Quies": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, XBP1, FOXA1, RBFOX2, LEO1, TSC22D4, THRB, ZFP64, PRDM1, ZNF189, PAX5, MZF1, MITF, MAF, TEAD1, BCLAF1, TRIM28, ZNF121, SNAI2, SMAD5, ESR1, OCA2, CTCF, JUN, TEAD4, PDX1, ZNF425, POU5F1, TOP2A, CTBP1, ZSCAN21, ZBTB17, ZBTB48, ZNF317, STAT1, ZMYND11, ERG2, ERG, PAX6, MYC, RFX1, RAD21, TOP1, APC, ZNF614, NKX3-1, NR3C1, CEBPB, KMT2A, EZH2, SPI1, GATA2, ZNF777, FLI1, HEXIM1-CDK9, NFIL3, ETV5, RUNX1, CEBPA, NKX2-2, AFF4, ZFX, ZNF770, ERG3, TRIM22, PRPF4, EWSR1, CDK6, GR, ARNT, BACH1, ATF2, ZEB2, SUPT5H, CDK8, CSNK2A1, ZEB1, PML, STAT5A, RBM22, BCL11A, CTBP2, FOXP1, ELL2, ZNF394, NFATC3, FOXA2, MTA3, PAF1, E2F8, ZNF600, NFATC1, ZBED1, WT1, ZBTB33, HOXB13, NEUROD1, SP140, HIF1A, OTX2, ZNF143, GATA1, AGO2, NCOA3, NR2F2, NR2F1, KDM5B, TP53, ZSCAN22, ZNF445, AR, ZBTB42, MYNN, JUND, ILF3, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): SH3BGR,ETS2,HMGN1,GET1-SH3BGR,GET1,LCA5L
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000157557,
ENSG00000205581,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
ENSG00000185437,
- Related loop:
chr21:38800000-38825000~~chr21:39325000-39350000,
chr21:39325000-39350000~~chr21:39425000-39450000,
chr21:39335976-39337473~~chr21:39387323-39389534,
chr21:39336013-39337477~~chr21:39387504-39389563,