Deatailed information for cohesin site CDBP00419468

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  • Basic information
  • CohesinDB ID: CDBP00419468
  • Locus: chr21-39343962-39344240
  • Data sourse: GSE67783, ENCSR153HNT
  • Cell type: K-562, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 0% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.978
  • Subunit: SA1
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 91% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "4_Tx": 69%, "5_TxWk": 28%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, NME2, FOXA1, RXRB, MLL4, KDM3A, ZBTB7B, HDGF, MEN1, THAP1, ZBTB44, IKZF3, MORC2, PAX5, TEAD1, ZNF121, LMO2, OCA2, PITX3, HDAC8, ZNF561, ARID5B, E4F1, SOX5, DEK, E2F4, ZNF528, RFX3, KMT2B, GATAD2A, NANOG, ZNF263, POU5F1, TOP2A, BRD3, CTBP1, ZMYND11, ERF, DUX4, STAT1, SAP130, ZNF485, ERG, ZBTB21, ZBTB8A, EZH1, SMARCA4, RFX1, TOP1, FOXK2, ZNF398, RCOR1, NR2F6, CD74, NFRKB, CEBPB, HNRNPL, CREB1, BMPR1A, GABPB1, ZHX2, ELF4, MIXL1, KLF17, GATA2, ZNF644, MXD3, FLI1, HCFC1, MXI1, DRAP1, RELB, EP400, RUNX1, CEBPA, HDAC1, NKX2-2, IRF3, SP5, TRIM22, SMARCC1, PRDM10, ZBTB2, TFDP1, SOX11, ZBTB10, ATF2, SP2, SMARCB1, TERF1, PML, PIAS1, SMAD1, C11orf30, EVI1, GSPT2, ARID2, IKZF5, RBM25, AFF1, MBD2, ELL2, HMGB1, ETV4, NFATC3, CBFA2T2, MEF2B, CBX3, ZNF207, CREM, CHD2, PAF1, NFATC1, ZSCAN16, WT1, MEF2C, CREB3L1, NEUROD1, JUNB, TCF4, MAF1, SPIB, PLAG1, KLF4, BCL11B, ZBTB6, MED, EGR2, ELF3, ARID4B, RXR, EGLN2, ZNF366, ZBTB26, HSF1, NCOR1, SCRT1, ILF3, ZNF316, FOSL1, ZNF660, XBP1, KDM4B, ZNF101, PBX2, HNRNPK, ATF3, THRB, ZC3H8, ZFP64, RUNX3, CBFB, DPF1, ZSCAN4, TP63, MITF, ZNF467, ZNF780A, MAF, JMJD1C, INTS11, ELF1, RBM39, SNAI2, KLF10, SMAD5, FUS, CTCF, TAF3, JUN, ZBTB20, MNT, LMO1, DPF2, RYBP, IRF4, ZNF350, PDX1, TFAP2C, RBPJ, MLX, ZSCAN21, ZBTB17, ZBTB48, MTA2, NONO, SRF, DDX5, NBN, PBX1, ONECUT1, ZNF2, KDM4A, HOMEZ, FOXP2, RXRA, NKX3-1, MIER3, LEF1, VDR, NR3C1, ESRRA, STAT5B, KMT2A, ZBTB11, TBL1XR1, KLF8, GRHL2, EBF3, ZKSCAN5, ZBTB14, ZSCAN29, SMARCA5, NFIL3, CC2D1A, THAP11, EZH2phosphoT487, SOX13, AFF4, ZNF770, ZMIZ1, ZNF18, SP3, ARNT, BACH1, ZNF48, PRDM9, ZEB2, NFYA, HMBOX1, PBX3, MAFB, NCAPH2, ZNF10, HMGXB4, ETV6, TEAD3, ZXDB, U2AF1, TAF7, KLF9, TBX5, USF1, SP1, BCL11A, TFAP2A, ZNF479, ATF7, ASH2L, GLIS2, PRDM6, ZNF623, SMC3, STAG1, MLLT1, ZNF394, TRP47, SAFB, AGO1, MTA3, EBF1, MAFF, ESR2, ZNF580, ZKSCAN1, KLF7, KDM1A, ZIC2, PCGF1, GATA3, TAL1, NRIP1, ZNF143, AGO2, MTA1, ZNF768, TP53, ZSCAN22, NFKB1, BRD2, PHF5A, KAT8, ARRB1, TBX21, EGR1, RB1, TFIIIC, RNF2, BRD4, SPIN1, JUND, CUX1, ZSCAN23, TBX2, ZNF468, PGR, FANCL, SOX2, PATZ1, LEO1, UBTF, RING1B, TFAP4, SIN3B, CHD7, ZNF444, ATF4, MXD4, ZNF189, SMARCE1, KLF6, NFE2L2, SAP30, ZNF217, ESR1, ZNF524, KLF1, SOX4, E2F6, TRIM24, RFX5, U2AF2, GTF2F1, GLIS1, POU2F2, ZSCAN5D, KDM4C, ZSCAN5A, ERG2, SP4, TBP, HOXC5, SMARCC2, ETS1, MYC, NKX2-1, MCRS1, GABPA, STAT3, IKZF1, ZNF343, SRSF3, EZH2, ZNF652, PHF8, SPI1, ZNF202, PCBP1, HDAC2, INTS13, GATAD2B, TAF9B, ZNF76, NFYB, ZNF554, ETV5, BCL6, SIN3A, ERG3, RARA, ZNF384, NFYC, CREBBP, TAF15, ZNF35, SMAD4, ZNF518A, CDK8, CSNK2A1, ZEB1, ZMYM3, NCOA1, SREBF2, RBM22, MAFK, HNF4A, NR4A1, REST, ARID1A, ZHX1, HNRNPLL, ZNF543, BCOR, FOXP1, AATF, NCOR2, CXXC4, PPARG, ZNF692, GTF2B, ZNF574, TCF7, FOXO3, RELA, TARDBP, SKIL, MAX, ZNF592, GFI1B, NR2F1, TCF7L2, KDM5B, PKNOX1, AR, ZNF324, HEXIM1, DMAP1, AHR, FOSL2, MBD3, ZNF391, HMG20A, E2F7, HMGN3, MEIS2, SUZ12, RBFOX2, SFMBT1, ZFHX2, CTCFL, PRDM1, KLF14, MECOM, CDX2, ZNF629, KLF5, THRAP3, TRIM28, BCLAF1, ETV1, RCOR2, MLL, USF2, ZFP91, TCF12, EP300, BAF155, GATA6, PRDM4, SOX6, RAD51, ZNF512B, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EHMT2, EED, CHD8, BRD1, MYCN, RUNX1T1, CDK7, ID3, GATAD1, GMEB2, ARID3A, ZNF585B, MIER1, ZNF341, RAD21, GRHL3, APC, XRCC5, ZNF614, NFE2, ZNF639, ZNF750, FEZF1, TRPS1, ZNF664, TFE3, EHF, IRF1, HBP1, ZGPAT, MRTFB, ZIM3, ATF1, PTBP1, MAFG, SMC1A, CBX1, SIRT6, ZNF335, ZFX, FIP1L1, SMAD3, IRF2, PRPF4, NOTCH1, BRD9, RUNX2, ZSCAN30, GATA4, OSR2, ZNF184, CDK6, SMAD2, NRF1, PBX4, SUPT5H, CHD1, FOS, MED1, KDM6B, MYB, SCRT2, CEBPD, VEZF1, ZNF3, L3MBTL2, KLF16, NIPBL, PHF20, ZBTB7A, CCNT2, PHIP, TCF3, ZNF783, PAX7, NELFA, SKI, KLF13, FOXA2, RBBP5, E2F8, ZNF600, MIER2, ZBED1, ZBTB33, CDK9, HOXB13, YY1, ZNF148, BRCA1, SP140, ZNF610, HIF1A, OTX2, ZNF519, ZNF740, ZNF449, GATA1, HAND2, CEBPG, SP7, NCOA3, NR2F2, ZNF512, ZNF687, ZNF213, NFKBIZ, BHLHE40, TAF1, ZNF579, ZBTB40, ZBTB42, NOTCH3, CLOCK, MAZ, ZNF24
  • Target gene symbol (double-evidenced CRMs): SH3BGR,GET1-SH3BGR,HMGN1,GET1,ETS2,LCA5L
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000157557, ENSG00000205581, ENSG00000285815, ENSG00000182093, ENSG00000157578, ENSG00000185437,
  • Related loop: chr21:38800000-38825000~~chr21:39325000-39350000, chr21:39313200-39315343~~chr21:39347346-39350688, chr21:39313201-39315232~~chr21:39347651-39350715, chr21:39313213-39315341~~chr21:39347106-39349452, chr21:39313217-39315223~~chr21:39347655-39350638, chr21:39313225-39315438~~chr21:39347557-39350333, chr21:39320997-39322719~~chr21:39347655-39350638, chr21:39325000-39350000~~chr21:39425000-39450000, chr21:39347365-39350526~~chr21:39387267-39389644, chr21:39347651-39350709~~chr21:39387578-39389687,
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