- Basic information
- CohesinDB ID: CDBP00419473
- Locus: chr21-39363116-39364202
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Data sourse: GSE206145-GSE177045, GSE67783, ENCSR000BKV, ENCSR879KXD, GSE206145-NatGen2015, ENCSR153HNT, GSE111537, GSE73207
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Cell type: MCF-7, Fibroblast, TF-1, K-562, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 63%,
"14_ReprPCWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, SMC1A, CEBPA, RUNX1T1, ZFX, CTBP1, XBP1, MEIS2, PBX2, SP4, CDK9, ERG, KDM1A, RELA, CREBBP, LYL1, MYC, GRHL3, GATA3, GABPA, MECOM, TAL1, ETV6, XRCC5, NRIP1, ZNF143, NFE2, MED1, PLAG1, JMJD1C, NCOA3, ELF1, TRIM28, KMT2A, EZH2, LMO2, ESR1, TP53, OCA2, PKNOX1, ZIM3, EVI1, CTCF, TCF12, USF1, SPI1, BCL11A, GATA2, RXR, FLI1, NCOR1, NOTCH3, TCF3, SMC3, EED
- Target gene symbol (double-evidenced CRMs): BRWD1,PSMG1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops